Journal ArticleDOI
Serum mediated inhibition of cellular immunity to methylcholanthrene-induced murine sarcomas.
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TLDR
Serum from the tumor-bearing animals, obtained at the time of tumor removal and explantation into culture, abrogated the inhibitory effect of autochthonous lymph node cells (LNC), and serum taken before palpable tumors could be detected did not abrogate the inhibitedory LNC effect.About:
This article is published in Cellular Immunology.The article was published on 1970-05-01. It has received 187 citations till now. The article focuses on the topics: Cellular immunity & Methylcholanthrene.read more
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Book ChapterDOI
Immunologische Aspekte des Krebses
TL;DR: In den letzten Jahren rasch gewachsen, da immunologische Methoden auf vielen Gebieten der Krebsforschung angewandt werden.
Journal Article
Enhanced Tumor Growth Caused by Anti-Th-B Antiserum Due to a Possible Activation of Suppressor T-Cells
TL;DR: It is suggested that a precursor of suppressing cells carries the Th-B determinant and that anti-Th-B antibodies stimulate these precursor cells into mature active suppressor cells that depress the cellular immune mechanism involved in the rejection of Sarcoma 180 in AKR mice.
Journal ArticleDOI
Soluble tumor antigen‐induced lymphocyte proliferation: Effects of serum from normal and tumor‐bearing mice
TL;DR: The inhibitory effects of tumor‐bearing sera on lympho‐proliferative responses to soluble tumor antigens appear to be similar to the inhibition seen as “serum blocking” in other assays of tumor immunity.
Journal Article
Cancer immunotherapy with surgery.
Kunzo Orita,Hiroaki Miwa,Tetsuya Mannami,Eiji Konaga,Masahito Yumura,Hanzo Fukuda,Yoshio Uchida,Harutsugu Nakahara,Shigeo Hayashi +8 more
TL;DR: Cancer immunity, however weak, constitutes the basis for other treatments in selectively attacking cancer cells remaining after surgery, chemotherapy or irradiation, and should thus not replace chemotherapy or radiotherapy, but these methods should be employed in combination to attain more favorable results.
References
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Journal ArticleDOI
Immunity to methylcholanthrene-induced sarcomas.
Richmond T. Prehn,Joan M. Main +1 more
Book ChapterDOI
Cellular immunity against tumor antigens.
TL;DR: The demonstration of cellular immunity to TSTA implies that autochthonous neoplasms appear in the presence of immune lymph node cells, which can destroy their cells at least in vitro .
Journal ArticleDOI
Cellular and Humoral immunity to Different Types of Human Neoplasms
TL;DR: MOST experimentally induced animal neoplasms contain tumour specific transplantation antigens (TSTA), against which immunological reactions can be detected both in vivo and in vitro.
Journal ArticleDOI
Studies on cellular immunity and its serum mediated inhibition in Moloney-virus-induced mouse sarcomas.
TL;DR: A colony‐inhibition technique was used to demonstrate lymph‐node cell (LNC) mediated immune reactions against tumor‐specific transplantation antigens of primary, Moloney sarcoma virus induced mouse sarcomas.
Journal ArticleDOI
Immune response to urinary bladder tumours in man.
TL;DR: A microassay in disposable tissue culture plates was used to demonstrate a cell‐mediated immune response against human urinary bladder carcinoma and no significant cytotoxic effects were produced by control leukocyte suspensions from a patient with prostatic carcinoma, from patients with non‐neoplastic diseases or from normal healthy individuals.