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Journal ArticleDOI

Sexualhormone VII. Über die künstliche Herstellung des Testikelhormons Testosteron (Androsten-3-on-17-ol)

L. Ruzicka, +1 more
- 01 Jan 1935 - 
- Vol. 18, Iss: 1, pp 1264-1275
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This article is published in Helvetica Chimica Acta.The article was published on 1935-01-01. It has received 143 citations till now.

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Journal ArticleDOI

A Review of the Chemistry, Biological Action, and Clinical Applications of Anabolic-Androgenic Steroids

TL;DR: Given the biological effects and potential adverse effects of AAS, administration of these agents should be avoided in pregnant women, women with breast cancer or hypercalcemia, men with cancers of the prostate or breast, and patients with nephrotic syndromes or significant liver dysfunction.
BookDOI

Testosterone : action, deficiency, substitution

TL;DR: The book begins with the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs, and the possible role of androgens in the development of prostatic hypertrophy and carcinoma.
Journal ArticleDOI

Androgens, Brain, and Behavior

TL;DR: Data from both animals and humans suggest that the biological and behavioral responses to androgens are context-dependent, which is further suggested by gender-related differences in pharmacokinetics/pharmacodynamics.
Journal ArticleDOI

Metabolism of anabolic androgenic steroids.

TL;DR: A review of the metabolism of AAS is presented and Testosterone is the principal androgenic steroid and its metabolism is compared with that of Aas.
Journal ArticleDOI

Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: a looming public health concern?

TL;DR: Long-term use of supraphysiologic doses of AAS may cause irreversible cardiovascular toxicity, especially atherosclerotic effects and cardiomyopathy, while in other organ systems, evidence of persistent toxicity is more modest, and interestingly, there is little evidence for an increased risk of prostate cancer.
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