Journal ArticleDOI
Silica-bonded chiral stationary phases with structurally simple π-donor chiral selectors for high-performance liquid chromatography
TLDR
In this paper, seven chiral stationary phases obtained from (S )-phenylalanine derivatives, ( R )-Mosher's acid and ( S )-naproxen were prepared and evaluated.About:
This article is published in Journal of Chromatography A.The article was published on 1992-01-10. It has received 22 citations till now. The article focuses on the topics: Chiral derivatizing agent & Chiral column chromatography.read more
Citations
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Journal ArticleDOI
Multiple dual-mode countercurrent chromatography applied to chiral separations using a (S)-naproxen derivative as chiral selector.
TL;DR: In this paper, MDM has been applied to the chiral CCC separations of two racemic mixtures, using (S)-naproxen N,N-diethylamide as chiral selector (CS) and improved resolution factors were successfully obtained.
Journal ArticleDOI
Evaluation of new chiral stationary phases of bonded cyanuric chloride with amino acid and naphthylalkylamine substituents for liquid chromatographic separation of amino acids and amino alcohols as dinitrobenzoyl derivatives
TL;DR: Chiral stationary phases (CSPs) with two chiral centers derived from (RS)-phenylalanyl- and (S)-1-(1-naphthyl)ethylamino-disubstituted cyanuric chloride and corresponding stationary phases containing one chiral center, by replacing a substituent group attached to the asymmetric center with hydrogen, were prepared for evaluating the enantioseparation of amino acid and amino alcohols as dinitrobenzoyl derivatives as discussed by the authors.
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Retention of fluorinated chiral selectors in biphasic fluorinated solvent systems and its application to the separation of enantiomers by countercurrent chromatography
TL;DR: The applicability of the ENFB/2-PrOH/H(2)O mixture to the separation of enantiomers, in combination with a fluorinated chiral selector (CS), was evaluated and enantioselectivity was maintained in the fluorinated solvent system without compromising eluting time.
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Doubly tethered tertiary amide selectors: Modified version of Doyle et al.'s naproxen chiral stationary phase
TL;DR: Doyle et al. as mentioned in this paper proposed a chiral stationary phase (CSP) that avoids the presence of amide hydrogen which often serves to increase retention, attenuate enantioselectivity and diminish the efficiency of the CSP.
Journal ArticleDOI
Improved chiral stationary phase derived from (S)-naproxen for the liquid chromatographic resolution of enantiomers
TL;DR: In this article, an (S)-naproxen-derived chiral stationary phase (CSP) containing a tertiary N-phenyl amide linkage was prepared.
References
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Considerations of chiral recognition relevant to the liquid chromatography separation of enantiomers
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Techniques de remplissage de colonnes de chromatographie liquide à haute performance avec des microparticules poreuses
TL;DR: In this paper, column parameters (length and internal diameter) were studied and a study of column parameters showed that an internal diameter of 4.6 mm gave the best results with the injection system used.
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High-performance liquid chromatographic separation of enantiomers on (S)-1 -(α-naphthyl)ethylamine bonded to silica gel
TL;DR: Preparation de deux nouvelles phases chirales et application a la separation d'amines, aminoacides et acides carboxyliques enantiomeres as discussed by the authors.
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Enantiomer separation of pyrethroid insecticides by high-performance liquid chromatography with chiral stationary phases
TL;DR: In this article, the separation of enantiomers of pyrethroid insecticide esters by high-performance liquid chromatography was studied using some recently developed chiral stationary phases.
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Elution orders in the separation of enantiomers by high-performance liquid chromatography with some chiral stationary phases
TL;DR: In this paper, the authors investigated the mechanism of enantiomer separation in high-performance liquid chromatography with some urea derivatives containing two asymmetric carbon atoms attached to two nitrogen atoms of the urea group derived from (S )- or ( R )-valine (Val) and (S)- or (R )-1-(α-naphthyl)ethylamine (NEA) as chiral stationary phases (CSPs) and showed that two kinds of diastereometric interactions are produced and each of the two chiral centres may