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Patent

Skin external agent

TLDR
In this article, the α-tocopheryl retinoate is added to a water-in-oil type emulsion system in an amount of 0.001-10wt.
Abstract
PURPOSE: To obtain a skin external agent remarkably improved in the stability of α-tocopheryl retinoate by adding the α-tocopheryl retinoate to a water-in-oil type emulsion system. CONSTITUTION: This skin external agent improved in the stability of the α- tocopheryl retinoate as an ingredient effective for preventing and treating skin hyperkeratosis, etc., and preventing and recovering skin aging is prepared by adding the α-tocopheryl retinoate to a water-in-oil type emulsion system comprising an oil component such as liquid paraffin or squalane, an aqueous phase component and a surfactant. The α-tocopheryl retinoate is preferably added in an amount of 0.001-10wt.%, especially 0.01-2.0wt.%, and the oil phase component is also preferably added in an amount of 10.0-50wt.%. The surfactant includes diglycerol dioleate and diglycerol diisostearate. Main additives to be added to the aqueous phase component are glycerol, butylene glycol, etc. The skin external agent is stable against heat, etc., and is little in the deterioration of the activity even when stored for a long period of time. COPYRIGHT: (C)1996,JPO

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