Fig. 4. Effect of uteroplacental insufficiency and cross-fostering on skeletal muscle myogenic regulatory and growth factors. Hindlimb skeletal muscle myogenic differentiation 1 (MyoD), myogenin, myogenic regulatory factor 4 (MRF4) and insulin-like growth factor 1 (IGF-I) mRNA relative to b-actin in male (a–d, respectively) and female (e–h, respectively) offspring at postnatal day 7. Control and Restricted offspring were fostered onto a different Control or Restricted mother to yield four experimental groups (pup-on-mother): Cont-on-Cont, Cont-on-Rest, Rest-on-Cont and Rest-on-Rest. Values are mean6 S.E.M. (n5 7–10/group). *Denotes significantly (P, 0.05) different from Cont-on-Cont. ‘#’ denotes significantly (P, 0.05) different from Cont-on-Rest.
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