Stress response and its relationship to cystic (pseudofollicular) change in the definitive cortex of the adrenal gland in stillborn infants.
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It is argued that cystic (pseudofollicular) change in the adrenal cortex of the newborn signifies a previous stress reaction.Abstract:
The adrenal glands of 41 fresh stillbirths were studied and a 'stress response' pattern could be seen in 28. In these glands the stress response was characterised by compact cell change, lipid depletion, excess pyroninophilia, and dilatation of the very prominent granular endoplasmic reticulum. Scattered areas of cytolysis of cells, especially of the definitive cortex, gave rise to the commonly seen cystic (pseudofollicular) change and it was obvious that cells undergoing lysis were severely 'stressed'. In 2 infants there was a 'clear cell reversal' pattern. Histological and ultrastructural changes of the stress response were not identified in 11. Infants of low birthweight score were somewhat more commonly represented in the group that did not show a stress response. Cytolytic changes accompanying a stress response were commoner in immature infants. It is argued that cystic (pseudofollicular) change in the adrenal cortex of the newborn signifies a previous stress reaction.read more
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Journal ArticleDOI
The fetal adrenal gland: lipid distribution with associated intrauterine hypoxia
Warick Delprado,P.J. Baird +1 more
TL;DR: The adrenal glands of 134 fetuses, either stillborn or dying within 24 h, were studied to ascertain the lipid droplet pattern in the fetal cortex and the findings were correlated with the associated placental pathology and clinical features.
Journal ArticleDOI
Investigation of stillbirth.
TL;DR: This outline attempts to identify an approach to the examination of the stillborn and accompanying placenta, with appropriate use of ancillary studies that may uncover the cause of death and/or identify factors that could prejudice future pregnancies.
Journal ArticleDOI
Association between Pulmonary Hypoplasia and Hypoplasia of Arcuate Nucleus in Stillbirth
Luigi Matturri,Anna Maria Lavezzi,Iolanda Minoli,Giulia Ottaviani,Barbara Rubino,Anna Cappellini,Lino Rossi +6 more
TL;DR: It is demonstrated that in about a third of stillbirths there is a congenital hypodevelopment of both lung and arcuate nucleus and in these cases the ARCn hypoplasia would exert a negative effect on respiratory movements in utero and therefore on lung development.
Book ChapterDOI
The adrenal cortex in the fetus and neonate
TL;DR: The characteristic zonal morphology of the fetal cortex reflects a response to the necessarily high levels of plasma adrenocorticotropic hormone (ACTH), as a reduction in ACTH release is consistently followed by rapid adrenal involution.
References
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Journal ArticleDOI
Intrauterine growth of live-born Caucasian infants at sea level: Standards obtained from measurements in 7 dimensions of infants born between 25 and 44 weeks
TL;DR: Normal anthropometric standards are presented for new-born Caucasian infants at sea level between 25 and 44 weeks' gestational age based upon measurements in 7 dimensions made in duplicate by a single observer using standard measurement techniques.
Journal ArticleDOI
Premature delivery of foetal lambs infused with glucocorticoids.
TL;DR: Parturition induced by dexamethasone was not delayed by administration of 100 mg.
Journal ArticleDOI
Accelerated appearance of pulmonary surfactant in the fetal rabbit.
R V Kotas,M E Avery +1 more
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