Journal ArticleDOI
Surgery for colorectal cancer metastatic to the liver. Optimizing the results of treatment.
TLDR
Overall, hepatic resection appears to be an important means of curing patients with metastatic colorectal cancer isolated to the liver, and it seems imperative that all patients with hepatic metastases be evaluated by an experienced hepatic surgeon for a curative resection.About:
This article is published in Surgical Clinics of North America.The article was published on 1989-04-01. It has received 242 citations till now. The article focuses on the topics: Primary tumor & Colorectal cancer.read more
Citations
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Journal ArticleDOI
Resection of colorectal liver metastases.
TL;DR: Using Cox's multivariate regression analysis, the presence of satellite metastases, primary tumor grade, the time of metastasis diagnosis diameter of the largest metastasis, anatomic versus nnanatomic approach, year of resection, and mesenteric lymph node involvement each independently affected both crude and tumor-free survival.
Journal ArticleDOI
Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer
Nancy E. Kemeny,Ying Huang,Alfred M. Cohen,Weiji Shi,John A. Conti,Murray F. Brennan,Joseph R. Bertino,Alan D. Turnbull,Deidre Sullivan,J. Stockman,Leslie H. Blumgart,Yuman Fong +11 more
TL;DR: For patients who undergo resection of liver metastases from colorectal cancer, postoperative treatment with a combination of hepatic arterial infusion of floxuridine and intravenous fluorouracil improves the outcome at two years.
Journal ArticleDOI
Hepatic metastases from colorectal carcinoma: Impact of surgical resection on the natural history
TL;DR: Radical excision of colorectal secondaries to the liver therefore offers effective palliation, and in a small number the chance of a cure.
Journal ArticleDOI
Surgical resection of hepatic metastases from colorectal cancer: a systematic review of published studies.
TL;DR: It is clear that there is group of patients with liver metastases who may become long-term disease- free survivors following hepatic resection, and whether the addition of adjuvant treatments results in improved survival is needed.
Journal ArticleDOI
Surgical margin in hepatic resection for colorectal metastasis: a critical and improvable determinant of outcome.
Blake Cady,Roger L. Jenkins,Glenn Steele,W D Lewis,Michael D. Stone,William V. McDermott,J. M. Jessup,Albert Bothe,Peter Lalor,E. J. Lovett,Phillip T. Lavin,David C. Linehan +11 more
TL;DR: Surgical resection or cryotherapy of hepatic metastasis from colorectal cancer is safe and curable in appropriately selected patients and surgical margin governs the patterns of failure and outcome in potentially curable patients.
References
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Journal Article
Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of patterns of recurrence.
Kevin S. Hughes,Simon R,Songhorabodi S,Martin A. Adson,Duane M. Ilstrup,Joseph G. Fortner,Barbara J. Maclean,James H. Foster,John M. Daly,Fitzherbert D +9 more
TL;DR: Hemodial resection effectively controls hepatic tumor in a substantial number of patients, adjuvant therapy after hepatic resection should be directed at both the lung and liver to significantly increase survival, and patients with positive pathologic margins or bilobar metastases are at an increased risk for hepatic recurrence.
Journal Article
Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of indications for resection
TL;DR: The overall 5-year survival rate for this large series has been very satisfying, and decision making in the future must take into account such factors as number of metastases, extrahepatic involvement, and stage of the primary tumor.
Journal ArticleDOI
Patterns of failure after surgical cure of large liver tumors. A change in the proximate cause of death and a need for effective systemic adjuvant therapy.
Glenn Steele,Robert T. Osteen,Richard Wilson,David C. Brooks,Robert J. Mayer,Norman Zamcheck,Thanjavur S. Ravikumar +6 more
TL;DR: These data confirm that major liver resection can be performed with minimum postoperative mortality (4.7 percent in this series) and the majority of patients were cured of their liver metastases.