Journal ArticleDOI
Synthesis, antibacterial and computational studies of Halo Chalcone hybrids from 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethan-1-one
TLDR
In this paper, a series of 6 1,4-benzodioxan-6-yl substituted chalcone derivatives were synthesized by the base-catalyzed Claisen-Schmidt reaction of the 1-(2,3-dihydrobenzo[b][1,4]dioxin-6]-ethan-1-one with fluoro and chloro substituted aromatic aldehydes.About:
This article is published in Journal of the Indian Chemical Society.The article was published on 2021-04-01. It has received 15 citations till now. The article focuses on the topics: Density functional theory.read more
Citations
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Journal ArticleDOI
Microwave prompted solvent-free synthesis of new series of heterocyclic tagged 7-arylidene indanone hybrids and their computational, antifungal, antioxidant, and cytotoxicity study.
Vishnu A. Adole,Rahul A. More,Bapu S. Jagdale,Thansing B. Pawar,Santosh S. Chobe,Rahul A. Shinde,Sunil L. Dhonnar,Prashant Bhimrao Koli,Arun V. Patil,Abhijit R. Bukane,Rajesh N. Gacche +10 more
TL;DR: In this article, the authors reported the expeditious synthesis of ten new antifungal and antioxidant agents containing heterocyclic linked 7-arylidene indanone moiety.
Journal ArticleDOI
Synthesis, Computational, Antibacterial and Antifungal Investigation of Two Tri-Fluorinated Chalcones of 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethan-1-one
TL;DR: In this article, the combined experimental and computational study along with antimicrobial screening of two tri-fluorinated chalcones from 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl) was reported.
Journal ArticleDOI
Design, fabrication, antitubercular, antibacterial, antifungal and antioxidant study of silver doped ZnO and CuO nano candidates: A comparative pharmacological study
Rohit S. Shinde,Rahul A. More,Vishnu A. Adole,Prashant Bhimrao Koli,Thansing B. Pawar,Bapu S. Jagdale,Bhatu Shivaji Desale,Yuvaraj P. Sarnikar +7 more
TL;DR: In this article, the authors used XRD, HR-SEM, EDAX, and HR-TEM spectral analyses to establish the structural characteristics of the synthesized NPs.
Journal ArticleDOI
PEG-400 mediated synthesis, computational, antibacterial and antifungal studies of fluorinated pyrazolines
TL;DR: In this article, the authors explored a detailed comprehensive study on the computational, antibacterial and antifungal studies of pyrazoline derivatives, and the molecular structure, optimized geometrical parameters, UV and vibrational assignments were established by the density functional theory (DFT); the Becke-3-Lee-Yang-Parr (B3LYP) functional with 6-311++G(d,p) basis set.
Journal ArticleDOI
Use of Pyrimidine and Its Derivative in Pharmaceuticals: A Review
TL;DR: The focus of this review is on research on various pharmaceuticals activities of pyrimidine analogs that has recently been published in the scientific literature.
References
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Gaussian 03, Revision E.01.
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TL;DR: In this article, the recent concepts of absolute electronegativity, {chi}, and absolute hardness, {eta}, are briefly reviewed and experimental results for a large number of molecules and radicals are presented.
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Susceptibility Test Methods: Dilution and Disk Diffusion Methods*
TL;DR: This chapter describes reference dilution and disk diffusion antimicrobial susceptibility test methods for nonfastidious, aerobic bacteria and the procedure for performing each test type as well as quality control procedures.
Journal ArticleDOI
Exploring Pharmacological Significance of Chalcone Scaffold: A Review
TL;DR: A review of the pharmacological activity of naturally occurring and synthetic chalcones, which highlights more recent pharmacological screening of these compounds, their mechanisms of action and relevant structure-activity relationships.
Journal ArticleDOI
Chalcone Derivatives: Promising Starting Points for Drug Design.
Marcelo N. Gomes,Eugene N. Muratov,Maristela Pereira,Josana de Castro Peixoto,Lucimar Pinheiro Rosseto,Pedro Cravo,Carolina Horta Andrade,Bruno J. Neves,Bruno J. Neves +8 more
TL;DR: This review summarizes current methodological developments towards the design and synthesis of new chalcone derivatives and state-of-the-art medicinal chemistry strategies (bioisosterism, molecular hybridization, and pro-drug design) and presents successful examples of the use of chalcones.