Journal ArticleDOI
The biochemistry of zinc
TLDR
The biochemistry of zinc is now beginning to be understood as discussed by the authors, and a deep knowledge of the chemistry of the element is known to the world, and the potential of zinc in catalysts has been found.About:
This article is published in Polyhedron.The article was published on 1987-01-01. It has received 61 citations till now.read more
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Journal ArticleDOI
The Essential Toxin: Impact of Zinc on Human Health
TL;DR: Rather than being a toxic metal ion, zinc is an essential trace element and plays a significant role in cytotoxic events in single cells in the brain, and cytotoxicity in consequence of ischemia or trauma involves the accumulation of free zinc.
Journal ArticleDOI
Function and mechanism of zinc metalloenzymes.
TL;DR: These studies demonstrate that the chemical nature of the direct ligands and the structure of the surrounding hydrogen bond network are crucial for both the activity of carbonic anhydrase and the metal ion affinity of the zinc-binding site.
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Toward the development of metal-based synthetic nucleases and peptidases: a rationale and progress report in applying the principles of coordination chemistry
Eric L. Hegg,Judith N. Burstyn +1 more
TL;DR: Recently, there has been a great interest in designing small metal complexes which are capable of catalytically hydrolyzing deoxyribonucleic acid (DNA), ribonuclear acid (RNA), and protein this article.
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The role of zinc in caspase activation and apoptotic cell death
TL;DR: The purpose of this review is to integrate previously published knowledge on Zn and apoptosis with current attempts to elucidate the mechanisms of action of this biometal, and examine the cytoprotective functions of Zn which suppress major pathways leading to apoptosis, as well as the more direct influence of ZN on the apoptotic regulators, especially the caspase family of enzymes.
Journal ArticleDOI
Coordination compounds of copper, nickel and iron with Schiff bases derived from hydroxynaphthaldehydes and salicylaldehydes
TL;DR: In this paper, a review describes Schiff bases of potential biological interest; for example, nickel compounds have been used in jack beam urease and in some hydrogenases, and the use of these compounds in catalytic reactions has also been considered.