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The cycle of Trypanosoma cruzi in tissue culture of embryonic heart muscle
Charles A. Kofoid,F. D. Wood,Ethel McNeil +2 more
- Vol. 41, Iss: 3
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The article was published on 1935-01-01 and is currently open access. It has received 27 citations till now. The article focuses on the topics: Tissue culture & Embryonic heart.read more
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Journal ArticleDOI
Cultivation of Clinically Significant Hemoflagellates
TL;DR: This review focuses on the hemoflagellates that infect humans, describing stages in the development of media leading to the fully defined formulations that are now available for the cultivation of many of these organisms.
Journal ArticleDOI
Trypanosoma cruzi: interaction with vertebrate cells in vitro. 1. Individual interactions at the cellular and subcellular levels.
James A. Dvorak,Thomas P. Hyde +1 more
TL;DR: Individual interactions between Trypanosoma cruzi trypomastigotes and vertebrate cells were observed in vitro as a continuous function of time under highly controlled environmental conditions and form the basis for a description of the complete intracellular cycle of T. cruzi in susceptible vertebrates.
Journal ArticleDOI
Cultivation of Trypanosoma cruzi in irradiated muscle cells: improved synchronization and enhanced trypomastigote production
D. M. Schmatz,P. K. Murray +1 more
TL;DR: A culture system was devised in which host cell mitosis was inhibited by irradiation prior to parasite infection and it proved possible to have virtually 100% of cells infected and achieve much better synchronization of trypomastigote release than with conventional culture systems.
Journal ArticleDOI
The morphology and life cycles of trypanosomes.
TL;DR: In 1936 Hoare (1936a) published an excellent outline of the classification of mammalian trypanosomes, and this classification is appropriate, therefore, to use this classification as a basis for the present review.
Journal ArticleDOI
Trypanosoma cruzi: Interaction with vertebrate cells in vitro: II. Quantitative analysis of the penetration phase
Thomas P. Hyde,James A. Dvorak +1 more
TL;DR: It was found that the parasites are distributed among host cells in a manner described by the negative binomial distribution, and the rate at which trypomastigotes penetrate bovine embryonic skeletal muscle cells (BESM) decreased exponentially in time in this system.
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C. Romaña,H. Meyer +1 more