Showing papers in "Experimental Parasitology in 1970"

TL;DR: Salivarian trypanosomes were separated from infected blood by adsorbing the particulate blood components on to DEAE-cellulose columns and eluting the trypanOSomes, confirming previous observations, cyclically transmitted isolations behaving similarly to those which were mechanically transmitted.

TL;DR: Eimeria maxima and E. brunetti were found to be the most difficult species to score since the gross pathologic picture has been difficult to correlate with weight gains or other indications of pathogenicity.

TL;DR: Analysis of the counts obtained from 6 flocks of birds showed the frequency distribution of the number of oocysts counted per sample to be log-normal, thus permitting a comparison of the level of infection in different groups of birds.

TL;DR: An electron microscope study of the vitelline follicles of Fasciola hepatica indicates that they are composed of cells in various stages of cytomorphosis, and it is suggested that the nurse cells may have a role in the selection and transport of materials necessary for the protein secretory and glycogen storage functions of theviteLLine cells.

TL;DR: Monoxenic cultures of Giardia trophozoites from the rabbit, chinchilla and cat have been established with Saccharomyces cerevisiae, in medium containing yeast extract, for more than a year.

TL;DR: Monkeys sensitized with dead schizont-infected cells in Freund's complete adjuvant, providing they survived the initial parasitemia after challenge, rapidly cleared their infection to give an immunity also effective against the other strain of P. knowlesi, although not against other species of Plasmodium.

TL;DR: The performance index for Novastat was 287 and forNovastat-3 it was 291, compared with an index of only 99 for the nonmedicated-infected controls, proving both products to be very effective in the prevention and control of Eimeria tenella infection in chicks.

TL;DR: Protection against homologous challenge with Plasmodium berghei was transferred from recovered to normal inbred August rats with serum but more effectively with cells, in normal and immune cell recipients.

TL;DR: Sera from monkeys sensitized with drug-suppressed infections contained intrastrain variant-specific agglutinins and opsonins for schizont Infected cells, and partially inhibited parasite multiplication in vitro; no evidence of lysins for 51Cr-labeled schizont-infected cells was obtained.

TL;DR: Results suggest that in the FCA-sensitized monkeys there is a delayed hypersensitivity to malarial antigens, although it is not known if this is involved in the protective mechanisms associated with sensitization with schizontinfected cells in Freund's complete adjuvant.

TL;DR: C- Chlorella protein was used as a marker to avoid the uncertainties of the conventional N balance study of protein digestibility and there was a small but statistically significant fall in the mean mucosal dipeptidase activities in infected sheep compared with the greater depression of activity reported previously for other enzymes in rats with nippostrongylosis.

TL;DR: Formation and function of the cytochrome system in Trypanosomatidae is an attractive target for drugs and the future development of effective trypanocides is bound up with rigorous biochemical studies.

TL;DR: The role of bacteria apparently was more vital for the survival of Heterakis than Histomonas in the pathogenesis of infectious enterohepatitis and the essential contributing factor was determined to be neither a favorable pH nor an oxidation-reduction potential value within the intestine of the host.

TL;DR: Antisera from rabbits which had been infected orally several times with eggs of A. suum demonstrated antigens in second and third stage larvae that were absent in adults, and the significance of these findings is discussed in terms of immunodiagnosis of ascariasis and the origin of protection-inducing antIGens during infection with A.suum.

TL;DR: The cell-mediated delayed hypersensitivity granulomatous reaction which develops around S. mansoni eggs appears to be a stage-specific reaction.

TL;DR: The P. knowlesi parasite is capable of accumulation of specific amino acids from outside the red blood cell, and the incorporation of 14C-amino acids into protein by uninfected blood was negligible, in general, compared to the incorporation by infected cells.

TL;DR: Differences in passive cutaneous anaphylactic antibody reactions among animals of a given species could not be attributed to differences in worm burdens, organ involvement, or egg excretion and correlated directly with the degree of resistance to the various species studied.

TL;DR: Recovery in rats infected with Plasmodium berghei was due primarily to acquired immunity that is effective without phagocytic hyperactivity, indicating that recovery was due mainly to acquired Immunity without hyperactivity.

TL;DR: The body wall muscle is similar in structure to that of other nematodes but an increase in the number of muscle cells per intercordal sector from the first-stage juvenile to the adult is recorded and some doubt is therefore cast on the concept of cell constancy in nematode.

TL;DR: 5′- O -Sulfamoyladenosine is less toxic to mice than nucleocidin, and its therapeutic index could be raised by manipulating the dose regimen, and the most active compound tested was 100% curative with minimal toxicity to mice with early infections.

TL;DR: Serial propagation of avian coccidia in birds fed mash containing coccidiostats results in the acquisition of a resistance for the specific coccidisostat, which persists virtually unchanged when the resistant strains are passed serially through groups of unmedicated chickens.

TL;DR: It was found that trypanosomes have a prediliction to invade brown fat and became more reticulotropic due to the influence of the drugs on the host's defense system.

TL;DR: Infective larvae of H. schachtii, the sugar beet nematode, were treated with aqueous and oil solutions of selected steroids and sesquiterpene derivatives then placed on host plants for development, and only males were observed to manifest prodigious testicular development together with consequent morphological aberrations.

TL;DR: The presence of cytoplasmic protrusions, other than flagella, on trypanosomes has been demonstrated by electron microscope techniques, and their function is unknown but observations suggest that they are rapidly shed from thetrypanosome.

TL;DR: The results indicate the functioning of the glycolytic pathway in this worm which resembles Schistosoma mansoni, a lactic acid producer, in the differential activities of the terminal enzymes of the pathway.

TL;DR: Methods of obtaining uniform and adequate exposure of chickens to coccidia in floor-pen experiments have been demonstrated and all experimental and reference drugs protected the chickens against the litter oocyst exposure, allowing greater body weight gains and better feed conversion than withdrawal or nonmedicated controls.

TL;DR: Reactions to single vaccination were related to the numbers of MS used; only one of the 51 inoculated animals died from the disease after vaccination, and reactions to the vaccine were minimal.

TL;DR: A broad plateau of high activity within the range pH 3.0–6.0 using Michaelis buffer and an optimum at pH 4.0 was observed for homogenates of male and female worms, and no second peak was found in the alkaline range.

TL;DR: Substantial and sustained increases in glutamic-oxalacetic transaminase (GOT) and lactic dehydrogenase (LDH) were observed in infected turkeys after 9 and 12 days postinfection and in infected chickens if liver damage was present.

TL;DR: Comparison of forms obtained by the tissue culture experiments with blood forms found in early parasitemia of infected mice suggests that the same process occurs both in tissue cultures and in the vertebrate, and explains why the fast-moving slender forms are the first to appear in the peripheral blood.