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Journal ArticleDOI

The effects of long-term lead intoxication on the nervous system of the chicken.

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TLDR
A syndrome was produced characterized by a fall in motor response amplitude, spinal motor neuron degeneration, motor axonal loss and atrophy of muscle, similar to that seen in human motor neuron diseases.
About
This article is published in Neuroscience Letters.The article was published on 1989-07-03. It has received 19 citations till now. The article focuses on the topics: Motor neuron & Nervous system.

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Metal Concentrations in Cerebrospinal Fluid and Blood Plasma from Patients with Amyotrophic Lateral Sclerosis

TL;DR: The hypothesis that metals with neurotoxic effects are involved in the pathogenesis of ALS is supported as a pattern of multiple toxic metals is seen in ALS CSF.
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A meta-analysis of observational studies of the association between chronic occupational exposure to lead and amyotrophic lateral sclerosis

TL;DR: Previous exposure to lead may be a risk factor for ALS, and the risk of developing ALS among individuals with a history of exposure toLead was almost doubled and the attributable risk of ALS was estimated to be 5%.
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Metal distribution in tissues of free-range chickens near a lead-zinc mine in Kabwe, Zambia.

TL;DR: Concentrations of Pb, Cd, and other metals in tissues of 17 free-range and commercial broiler chickens from the Kabwe mining town in Zambia were determined and human consumers in Kabwe could be exposed to Pb and Cd in free- range chickens.
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Lead contamination of chicken eggs and tissues from a small farm flock.

TL;DR: Lead contamination of egg yolks and edible chicken tissues represents a potential public health hazard, especially to children repeatedly consuming eggs from contaminated family-owned flocks.
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The effect of chronic lead intoxication in mature chickens.

TL;DR: Lead-treated hens laid significantly more eggs during the period of observation of nearly 3 years because of the increased frequency of laying cycles, which was almost three times that of control hens.
References
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Journal ArticleDOI

Micromethod for Lead Determination in Whole Blood by Atomic Absorption, with Use of the Graphite Furnace

TL;DR: Lead in blood can be accurately measured in as little as 20 mul of blood, hence the method is suitable for routine laboratory use and for pediatric screening.
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Retrograde axonal transport of lead in rat sciatic nerve.

TL;DR: The distribution of lead within the spinal cord indicated the possibility of retrograde axonal transport in the upper and lower motor neurons, which might explain how lead enters the central nervous system and could be related to the postulated role of lead in causing amyotrophic lateral sclerosis.
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Increased plasma levels of lead in patients with amyotrophic lateral sclerosis compared with control subjects as determined by flameless atomic absorption spectrophotometry.

TL;DR: The levels of lead in plasma were determined in 16 cases of amyotrophic lateral sclerosis and 18 control subjects, using flameless atomic absorption spectrophotometry, and the values in both groups are lower than reported earlier for normal subjects.
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