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Journal ArticleDOI

The papulonecrotic tuberculide. From Arthus reaction to lupus vulgaris.

J.G.L. Morrison, +1 more
- 01 Sep 1974 - 
- Vol. 91, Iss: 3, pp 263-270
TLDR
It is suggested that these tuberculides begin as an Arthus reaction which is followed by a delayed hypersensitivity response, which will prevent local proliferation of Mycobacterium tuberculosis in most cases, but in rare cases local multiplication of the organisms may lead to the development of lupus vulgaris.
Abstract
SUMMARY Ninety-one cases of papulonecrotic tuberculide were seen by the Department of Dermatology during the past 17 years. A focus of tuberculosis was found in 38%. Associated clinical phenomena included tuberculous arteritis with gangrene and the development of lupus vulgaris from papulonecrotic tuberculides. It is suggested that these tuberculides begin as an Arthus reaction which is followed by a delayed hypersensitivity response. The latter will prevent local proliferation of Mycobacterium tuberculosis in most cases, but in rare cases local multiplication of the organisms may lead to the development of lupus vulgaris. All patients improved rapidly on antituberculous treatment.

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Citations
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Book ChapterDOI

Diseases Caused by Bacteria

TL;DR: Disease of the sexual organs is considerably dangerous, because during this process, through adhesion and scarring of the epididymis or Fallopian tubes caused by inflammation, permanent sterility may occur.
Journal ArticleDOI

Etiology and management of genitourinary tuberculosis

TL;DR: Genitourinary tuberculosis (GUTB) is the second most common form of extrapulmonary tuberculosis, with more than 90% of cases occurring in developing countries and increasing rates of drug-resistant cases and co-infection with HIV.
Journal ArticleDOI

Lupus vulgaris. Clinical, histopathologic, and bacteriologic study of 10 cases.

TL;DR: Although different mechanisms could be implicated in the development of LV, an association with visceral tuberculosis is not infrequent and combined antituberculous therapy should be the treatment of choice in these patients.
Journal ArticleDOI

The histologic spectrumof the cutaneous mycobacterioses

TL;DR: The results indicate that a wide variety of cutaneous, clinical, and histologic guises may be assumed by mycobacterial infections in normal and immunocompromised hosts.
References
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Journal ArticleDOI

Histopathology of the Skin

TL;DR: Books and internet are the recommended media to help you improving your quality and performance.
Journal ArticleDOI

Anticomplementary effects and complement activity of human sera.

TL;DR: The probit transformation for the plotting of immune hemolysis produced by measured amounts of fresh human serum was found to be suitable for titration of complement and able of serum to become highly anticomplementary as a result of heating.
Journal ArticleDOI

The ills of man.

John H. Dingle
- 01 Sep 1973 - 
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