Showing papers in "Human Pathology in 1982"

TL;DR: Although sebaceous carcinomas elsewhere in the skin are rare, this study establishes that these neoplasms occur much more frequently in the ocular adnexa and have significant morphologic features that identify the more highly lethal carcinomas.

TL;DR: One hundred twenty-five pancreatic endocrine tumors were analyzed by immunocytochemistry using various antisera and found to contain cells immunoreactive to peptide(s) not causing clinical symptoms, and 54 of 30 "nonsecreting" tumors were shown to be multicellular.

TL;DR: The results reveal a correlation between the histopathologic grading in the initial biopsy and the clinical outcome: patients with mild (grade II) or moderate (grade III) lesions had a benign course or showed evidence of active disease without deterioration of renal function, whereas all patients who were followed for more than one year developed end-stage renal failure.

TL;DR: In this paper, a series of 3,432 cases of malignant melanoma of the choroid and ciliary body, mortality from metastasis 15 years after enucleation was 46 per cent.

TL;DR: The observed extent of microvascular occlusion supports a previously published theory that hypoxia is involved in the generation of hypertrophic scar and is greater in nonpatent vessels than in patent vessels.

TL;DR: The results of this study support the concept that MFH is a tumor of a dual fibroblastic-histiocytic origin.

TL;DR: It is proposed that this class of salivary gland tumor forms a spectrum with monomorphic adenoma and myoepithelioma at the extremes and a wide range of pleomorphicAdenoma between, depending on the type and degree of gene expression that is coupled with neoplastic transformation.

TL;DR: Kaposi's sarcoma is a neoplasm that usually affects persons who are in their fifties or older; it is more frequent in men than in women (ratio, 15:1) and is more c o m m o n in individuals o f Jewish (Ashkenazic) and Latin (Medi ter ranean) descent.

TL;DR: The clinical and pathologic aspects of 21 cases of mixed gonadal dysgenesis (MGD) were studied and it was suggested that patients with MGD be raised as females to prevent the development of gonadoblastoma and dysgerminoma.

TL;DR: Although the number of cases is too small to serve as a basis for firm conclusions, the lack of unequivocal correlation between the histologic features and clinical behavior is consistent with the unpredictable behavior of this neoplasm.

TL;DR: The authors propose that, in the future, pathologists label all adenoid cystic carcinomas as either "basaloid" or "nonbasaloids" and code each case accordingly, and suggest that this difference in survival was significant at the 0.0005 level.

TL;DR: Analysis of pulmonary fiber burden suggest that asbestos-related disease is not merely a matter of total numbers of fibers present, but that factors such as fiber type and size are equally important.

TL;DR: This is a clinicopathologic study of 17 cases of alveolar soft-part sarcoma of the orbit, with a distinctive organoid pattern outlined by thin-walled capillaries and an indolent clinical course.

TL;DR: Fibrous histiocytoma is the most common primary mesenchymal orbital tumor of adults, and the origin of the neoplasm is probably a primitive meschymal cell.

TL;DR: Identification of this pattern of cholestasis in liver biopsy specimens is useful in certain patients who may be a great risk of mortality and who require serous clinical attention directed toward elucidating a source for sepsis as well as aggressive management of other systemic disease.

TL;DR: Some of the previously described ultrastructural features of abnormal large-intestinal epithelium may be only the result of failure to compare the so-called abnormal cells with normal cells from the same region, as well as well-controlled studies of the abnormal epithelia of a particular segment of large intestine.

TL;DR: The immunostain for GFAP is useful in the diagnoses of astrocytic neoplasms and of mixed gliomas and the intensity of the stain were inversely proportional to the degree of malignancy.

TL;DR: Using monoclonal antibodies on frozen sections, the authors define the anatomic localization of T-lymphocyte subsets in follicular lymphomas as well as in nonneoplastic lymph nodes and tonsils.

TL;DR: This study is focused on the use of hybridoma-derived monoclonal antibodies, which are capable of detecting maturational stages of B and T cell differentiation and functionally distinct T cell subsets, in order to investigate the interactional and immunoregulatory defects that participate in the generation of the ocular adnexal lymphoid proliferations.

TL;DR: The morphologic diagnosis of deep mycoses, although ideally accomplished by culture, often has to be made from tissue sections for smears, when cultures are not available, and the use of special stains is absolutely necessary.

TL;DR: The authors conclude that the in vivo model that they describe, with its built-in controls, provides a valid approach for examining the dynamics of morphogenesis and cytodifferentiation in developing human genital tracts under experimentally regulated conditions.

TL;DR: It is shown that true adenoid cystic carcinomas do arise in different organs and knowledge of the specific ultrastructural features of adenoids cystic cancer can be useful in classifying these tumors in some cases.

TL;DR: In fetuses surviving intrauterine cytomegalovirus infection, inflammatory destruction of intrahepatic bile ducts could manifest as chronic cholestasis and paucity of bileducts later in infancy.

TL;DR: Eighteen patients with chondrosarcomas showing dedifferentiation were reviewed, and 13 of the 14 patients in whom there was follow-up died of their tumors, with an average survival of six months.

TL;DR: Observed Sertoli cells in these primary testicular disorders reflect a congenital deficiency producing abnormal development, and a transitional type of cell-from immature to mature-was observed.

TL;DR: The histologic pattern of tumor growth at tumor-nontumor boundaries was studied in 60 livers bearing hepatocellular carcinoma, and it was found that orcein-positive cells were hepatocytes blended with cancer cells.

TL;DR: It is concluded that the identification of intralymphatic cancerous emboli in mastectomy specimens is not a reliably reproducible prognostic finding on which recommendation of systemic chemotherapy in stage I breast carcinoma patients can be based.

TL;DR: The results indicate that a wide variety of cutaneous, clinical, and histologic guises may be assumed by mycobacterial infections in normal and immunocompromised hosts.

TL;DR: In 1,405 patients who died at the General Hospital of Trieste in 1974 and 1978, malignant neoplasm was revealed at autopsy, and clinical diagnosis was accurate in 54 per cent of these patients.