Journal ArticleDOI
The pharmacological management of chronic lower back pain.
Filippo Migliorini,Nicola Maffulli,Jörg Eschweiler,Marcel Betsch,Giovanni Catalano,Arne Driessen,Markus Tingart,Alice Baroncini +7 more
TLDR
Only baclofen, duloxetine, NSAIDs, and opiates showed to improve pain and disability levels in patients with LBP, but the patients’ demographics are heterogeneous, and the results must be interpreted with caution and in the light of possible adverse events connected to the use of these drugs.Abstract:
Treating chronic low back pain (LBP) can be challenging, and the most effective pharmacological therapy is controversial. The present systematic review investigated the efficacy of various pharmaco...read more
Citations
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Book Chapter
Depression and Pain
TL;DR: Depression and painful symptoms are closely related and commonly occur together; the prevalences of pain in depressed cohorts and depression in pain cohort are higher than when these conditions are individually examined.
Journal ArticleDOI
Systematic review of guideline-recommended medications prescribed for treatment of low back pain
Morgan Price,Zachary A. Cupler,Cheryl Hawk,Edward M. Bednarz,Sheryl Walters,Clinton J. Daniels +5 more
TL;DR: In this paper , the authors identify and descriptively compare medication recommendations among low back pain (LBP) clinical practice guidelines (CPGs) using PubMed, Cochrane Database of Systematic Review, Index to Chiropractic Literature, AMED, CINAHL, and PEDro.
Journal ArticleDOI
Entangled: A mixed method analysis of nurses with mental health problems who die by suicide.
TL;DR: Mental health/substance use, chronic illness, and chronic pain were seen to coexist in a complex, interdependent manner that appeared to be entangled in nurses' narratives before death.
Journal ArticleDOI
DANTE Study: The First Randomized, Double-Blind, Placebo and Active-Controlled, Parallel Arm Group Study Evaluating the Analgesic Efficacy and Safety of Dexketoprofen TrometAmol aNd Tramadol Hydrochloride Oral FixEd Dose Combination on Moderate to Severe Acute Pain in Patients with Acute Low Back Pain—Rationale and Design
TL;DR: The DANTE study as discussed by the authors was designed to comprehensively assess the analgesic efficacy and tolerability of dexketoprofen/tramadol (DKP/TRAM) 75/25 mg in a large cohort of patients with moderate to severe acute low back pain.
Journal ArticleDOI
Choosing the appropriate pharmacotherapy for nonspecific chronic low back pain
TL;DR: In this article , the authors provide an evidenced-based overview of the principles of pharmacological management of nonspecific chronic low back pain (NCLBP) aiming to restore daily activities and improve the quality of life.
References
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Journal ArticleDOI
The Oswestry Disability Index.
Jeremy Fairbank,Paul Pynsent +1 more
TL;DR: The ODI remains a valid and vigorous measure and has been a worthwhile outcome measure, and the process of using the ODI is reviewed and should be the subject of further research.
Journal ArticleDOI
CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016
TL;DR: This guideline is intended to improve communication about benefits and risks of opioids for chronic pain, improve safety and effectiveness of pain treatment, and reduce risks associated with long-term opioid therapy.
Journal ArticleDOI
Gastrointestinal Toxicity With Celecoxib vs Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis and Rheumatoid Arthritis: The CLASS Study: A Randomized Controlled Trial
Fred E. Silverstein,Gerald A. Faich,Jay L. Goldstein,Lee S. Simon,Theodore Pincus,Andrew Whelton,Robert W. Makuch,Glenn M. Eisen,Naurang M. Agrawal,William F. Stenson,Aimee M. Burr,William W. Zhao,Jeffrey D. Kent,James B. Lefkowith,Kenneth M. Verburg,G. Steven Geis +15 more
TL;DR: In this study, celecoxib, at dosages greater than those indicated clinically, was associated with a lower incidence of symptomatic ulcers and ulcer complications combined, as well as other clinically important toxic effects, compared with NSAIDs at standard dosages.
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