Journal ArticleDOI
The relationship between changes in REM sleep and clinical improvement in depressed patients treated with amitriptyline
J. Christian Gillin,J. Christian Gillin,Richard Jed Wyatt,Richard Jed Wyatt,David H. Fram,Frederick Snyder +5 more
Reads0
Chats0
TLDR
EEG sleep recordings were obtained on consecutive nights from six hospitalized depressed patients before, during, and after treatment with amitriptyline for a total of 370 nights of data, about 85% of all nights of the study.Abstract:
EEG sleep recordings were obtained on consecutive nights from six hospitalized depressed patients before, during, and after treatment with amitriptyline for a total of 370 nights of data, about 85% of all nights of the study. Amitriptyline significantly reduced time spent in rapid eye movement (REM) sleep and prolonged the REM latency throughout the treatment period. Three patients who improved during treatment showed a REM rebound when amitriptyline was discontinued, whereas three patients who did not improve showed no REM rebound.read more
Citations
More filters
Journal ArticleDOI
Sleep and Psychiatric Disorders: A Meta-analysis
TL;DR: Although no single sleep variable appeared to have absolute specificity for any particular psychiatric disorder, patterns of sleep disturbances associated with categories of psychiatric illnesses were observed.
Journal ArticleDOI
Sleep and depression--results from psychobiological studies: an overview.
TL;DR: Data indicate a strong bi-directional relationship between sleep, sleep alterations and depression, and most of the effective antidepressant agents suppress REM sleep.
Journal ArticleDOI
Improvement of Depression by REM Sleep Deprivation: New Findings and a Theory
TL;DR: It is suggested that the depressive abnormalities represent a "damaged," weakened sleep cycle "oscillator" and its correlate, a circadian rhythm disturbance, and that REM sleep deprivation improved depression to the extent that it stimulated the oscillator and corrected one manifestation of the circadian rhythm disturbances.
Journal ArticleDOI
Antidepressants and sleep: a qualitative review of the literature.
TL;DR: In general, the objectively measured sleep of depressed patients improves during 3–4 weeks of effective antidepressant treatment with most agents, as does their subjective impression of their sleep.
Journal ArticleDOI
Psychiatric disorders and sleep
TL;DR: Evidence that supports the view that the relationship between psychiatric disorders and sleep is complex and includes bidirectional causation is provided, reviewing data on sleep disturbances seen in patients with psychiatric disorders as well as data on the impact of sleep disturbances on psychiatric conditions.
References
More filters
Journal ArticleDOI
A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects.
TL;DR: Techniques of recording, scoring, and doubtful records are carefully considered, and Recommendations for abbreviations, types of pictorial representation, order of polygraphic tracings are suggested.
Book
Applied nonparametric statistics
TL;DR: In this paper, applied nonparametric statistics are applied to the problem of applied non-parametric statistical data collection in the context of the application of applied NN statistics, including:
Book
Applied nonparametric statistics
TL;DR: In this article, applied nonparametric statistics are applied to the problem of applied non-parametric statistical data collection in the context of the application of applied NN statistics, including: