Journal ArticleDOI
The treatment of patients with polycystic ovarian syndrome by in-vitro fertilization and embryo transfer: a comparison of results with those of patients with tubal infertility
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TLDR
IVF treatment may be a viable solution for polycystic ovarian syndrome patients resistant to an in-vivo protocol treatment regimes, and the fact that more oocytes are recovered from PCO patients, balances their lower fertilization and cleavage rates.Abstract:
Sixteen patients with polycystic ovarian syndrome (PCO) were treated by in-vitro fertilization (26 treatment cycles). The results were compared with 37 normo-ovulatory women with tubal disease (37 treatment cycles). The oestradiol and progesterone levels were higher during the follicular phase in the PCO patients, but were statistically significantly higher only on the day after human chorionic gonadotrophin administration. Although more oocytes were recovered per cycle from the PCO group (19.3 +/- 6.1) than from the control group (5.4 +/- 2.9) with P less than 0.004, the mean numbers of embryos per cycle were similar in both groups (3.7 +/- 2.4 versus 3.6 +/- 2.2, respectively). The pregnancy rate was also comparable in both groups (30.7 versus 29.7%, respectively). The fact that more oocytes are recovered from PCO patients, balances their lower fertilization and cleavage rates. We conclude, therefore, that IVF treatment may be a viable solution for PCO patients resistant to an in-vivo protocol treatment regimes.read more
Citations
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Journal ArticleDOI
Consensus on infertility treatment related to polycystic ovary syndrome
Thessaloniki,Greece. +1 more
TL;DR: The treatment of infertile women with polycystic ovary syndrome (PCOS) is surrounded by many controversies, and a group of experts reached a consensus regarding the therapeutic challenges raised in these women.
Journal ArticleDOI
Epidemiology and prevention of ovarian hyperstimulation syndrome (OHSS): a review
Annick Delvigne,Serge Rozenberg +1 more
TL;DR: Whether it is possible to identify patients at risk of ovarian hyperstimulation syndrome, and which preventive method should be applied when an exaggerated ovarian response occurs, is determined.
Journal ArticleDOI
Treatment options for polycystic ovary syndrome.
Ahmed Badawy,Abubaker Elnashar +1 more
TL;DR: Alternative medicine has been emerging as one of the commonly practiced medicines for different health problems, including PCOS, which underlines the contribution to the treatment of different symptoms.
Journal ArticleDOI
Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?
TL;DR: Animal models that mimic fetal androgen excess may provide unique insight into the origins of the PCOS syndrome, and the prenatally androgenized female rhesus monkey shows particular relevance to PCOS.
Journal ArticleDOI
The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance
Adam H. Balen,Lara C Morley,Marie Misso,Stephen Franks,Richard S. Legro,Chandrika N Wijeyaratne,Elisabet Stener-Victorin,Bart C.J.M. Fauser,Robert J. Norman,Helena J. Teede +9 more
TL;DR: The consensus guideline methodology is described, the evidence-based recommendations provided to the World Health Organisation (WHO) for their consideration in the development of global guidance are summarised and a narrative review on the management of anovulatory infertility in women with polycystic ovary syndrome is presented.