The treatment of rheumatoid arthritis and necrotizing vasculitis with penicillamine.
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This article is published in Arthritis & Rheumatism.The article was published on 1970-07-01 and is currently open access. It has received 122 citations till now. The article focuses on the topics: Necrotizing Vasculitis & Penicillamine.read more
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Therapeutic strategies for rheumatoid arthritis
Josef S Smolen,Günter Steiner +1 more
TL;DR: In this paper, the authors summarize the fruits of these advances: innovative approaches to the use of existing, traditional disease-modifying antirheumatic drugs; novel agents approved very recently; and further avenues that are presently under investigation or which are of more distant promise.
Journal ArticleDOI
The comparative efficacy and toxicity of second‐line drugs in rheumatoid arthritis results of two metaanalyses
TL;DR: Of the commonly used second-line drugs, AUR is the weakest, and injectable gold is the most toxic, and agents introduced in the future will be compared with these drugs.
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Intravenous cyclophosphamide plus methylprednisolone in treatment of systemic rheumatoid vasculitis
David G. I. Scott,Paul A. Bacon +1 more
TL;DR: Intravenous cyclophosphamide plus methylprednisolone is a useful early treatment for systemic rheumatoid vasculitis and results in more frequent healing of vasculitic lesions including leg ulcers and neuropathy, a lower incidence of relapse, fewer serious complications, and a lower mortality than did other treatments.
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Drug-induced taste and smell disorders. Incidence, mechanisms and management related primarily to treatment of sensory receptor dysfunction.
TL;DR: Treatment primarily requires restoration of normal sensory receptor growth, development and/or function and requires correction of steps initiating receptor and other pathology and includes zinc, theophylline, magnesium and fluoride.
References
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Modification of Parkinsonism--chronic treatment with L-dopa.
TL;DR: Slowly increasing oral doses of L-3,4-dihydroxyphenylalanine (L-dopa) induced at least partial improvement of some manifestations in a series of 28 patients with Parkinsonism.
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Rheumatoid factor, complement, and conglutinin aberrations in patients with subacute bacterial endocarditis*
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Collagen Defect Induced by Penicillamine
TL;DR: These findings reflect an abnormal pattern of collagen metdbolism, which is accompanied by an inhibition of wound-healing and by skin fragility.
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The induction of a rheumatoid factor-like substance in rabbits
TL;DR: The formation of a serum factor (RFLS) which resembled the human rheumatoid factor was a heat-stable protein that migrated electrophoretically in the gamma-beta globulin range and sedimented rapidly with ultracentrifugation.