Journal ArticleDOI
To pulse or not to pulse.
TLDR
Pulsatile and nonpulsatile blood flow have been intensely studied for cardiopulmonary bypass, isolated organ perfusion, and myocardial preservation and new methods to create pulsatile flow and their adaptation to the standard roller pump are discussed.About:
This article is published in The Annals of Thoracic Surgery.The article was published on 1978-03-01. It has received 128 citations till now. The article focuses on the topics: Pulsatile flow & Blood flow.read more
Citations
More filters
Journal ArticleDOI
Optimal Perfusion During Cardiopulmonary Bypass: An Evidence-Based Approach
TL;DR: There are currently limited data upon which to confidently make strong recommendations regarding how to conduct optimal CPB, and a critical need for randomized trials assessing clinically significant outcomes, particularly in high-risk patients.
Journal ArticleDOI
Renal autoregulation: new perspectives regarding the protective and regulatory roles of the underlying mechanisms
TL;DR: It is proposed that in addition to TGF-induced vasoconstriction, vasodepressor responses to reduced distal delivery may play a critical role in modulating afferent arteriolar reactivity to integrate the regulatory and protective functions of the renal microvasculature.
Journal ArticleDOI
Pulsatile and nonpulsatile cardiopulmonary bypass: review of a counterproductive controversy.
TL;DR: Failure to quantitate adequately the pulsatile components of flow in these studies prevents differentiation between effective and ineffective forms of pulsatile flow and makes comparison of studies difficult.
Journal ArticleDOI
Coronary artery bypass without cardiopulmonary bypass: analysis of short-term and mid-term outcome in 220 patients.
TL;DR: It is concluded that coronary artery bypass grafting without cardiopulmonary bypass can be done with relatively low operative mortality, although there seems to be an increased risk for early return of angina.
Journal ArticleDOI
Effect of cardiopulmonary bypass on the pharmacokinetics of drugs.
TL;DR: The effects of cardiopulmonary bypass on the pharmacokinetics of drugs are incompletely understood, and the subject merits further attention.
References
More filters
Journal ArticleDOI
Denaturation of plasma proteins as a cause of morbidity and death after intracardiac operations
Journal ArticleDOI
Effect of Pulse Pressure and Mean Arterial Pressure Modification on Renal Hemodynamics and Electrolyte and Water Excretion
TL;DR: Studies were conducted to evaluate the influence of pulsatile versus nonpulsatile arterial perfusion pressure on plasma flow, filtration rate, sodium excretion, and urine volume, and mechanisms by which modifications in salt and water excretion could result from alteration in the mean arterial pressure.
Journal ArticleDOI
Energy equivalent pressure.
TL;DR: In this article, the authors describe differences in steady and pulsatile blood flow in terms of an energy equivalent pressure, which is obtained by calculation from phasic flow and pressure measurements.