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Journal ArticleDOI

Transfer of antibiotic resistance from animal and human strains of escherichia coli to resident e. coli in the alimentary tract of man

H. Williams Smith
- 14 Jun 1969 - 
- Vol. 293, Iss: 7607, pp 1174-1176
TLDR
Antibiotic resistance was transferred to the resident Escherichia coli in the alimentary tract of a human being from cultures of E. coli of animal and human origin taken in large doses by mouth.
About
This article is published in The Lancet.The article was published on 1969-06-14. It has received 172 citations till now. The article focuses on the topics: Escherichia coli.

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Citations
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Journal ArticleDOI

Survival of Lactobacillus species (strain GG) in human gastrointestinal tract.

TL;DR: It is demonstrated that lactobacillus GG can survive and temporarily colonize the human gastrointestinal tract and can affect the metabolic activity of the resident microflora.
Journal ArticleDOI

Global epidemiology of CTX-M β-lactamases: temporal and geographical shifts in genotype.

TL;DR: Modifiable anthropogenic factors, such as poor access to basic sanitary facilities, encourage the spread of blaCTX-M and other antimicrobial resistance (AMR) genes, and justification for novel preventative and interventional strategies to reduce transmission of these AMR genes is provided.
Journal ArticleDOI

Transfer of multiple drug resistance plasmids between bacteria of diverse origins in natural microenvironments.

TL;DR: The present study demonstrates that conjugation and transfer of R plasmids is a phenomenon that belongs to the environment and can occur between bacterial strains of human, animal, and fish origins that are unrelated either evolutionarily or ecologically even in the absence of antibiotics.
Journal ArticleDOI

Bacterial resistance to antimicrobial agents used in fish farming: A critical evaluation of method and meaning

TL;DR: The contribution of R plasmids, selected in the aquatic environment, to the frequency of resistance in human pathogens is probably very small, and fish farmers will have to develop methods of husbandry that limit the rate at which resistant strains emerge.
Journal ArticleDOI

Escherichia coli Habitats, Cell Types, and Molecular Mechanisms of Gene Control

TL;DR: From this information, it is predicted that E. coli will have at least two phenotypically distinct cell types and that these will have dual molecular control mechanisms of opposite type for the regulation of certain functions.
References
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Journal ArticleDOI

The transmissible nature of the genetic factor in Escherichia coli that controls haemolysin production.

Smith Hw, +1 more
- 01 Apr 1967 - 
TL;DR: A genetic factor (designated Ent) responsible for enterotoxin production in six of 51 enterotoxigenic strains of Escherichia coli of porcine origin could be transmitted to other strains of E. coli and to Salmonella typhimurium and S. choleraesuis by conjugation in mixed culture.
Journal ArticleDOI

Observations on infective drug resistance in Britain.

H. W. Smith, +1 more
- 29 Jan 1966 - 
Journal ArticleDOI

Anti-microbial Drugs in Animal Feeds

Smith Hw
- 25 May 1968 - 
TL;DR: This article is based on a paper given at a symposium on “The Use of Drugs in Animal Feeds”, organized by the US National Research Council, Washington, DC, 1967.
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