Journal ArticleDOI
Triazolopyridines. Part 8.1 Nucleophilic substitution reactions of 5-bromo[1,2,3]triazolo[5,1-a]isoquinoline and 7-bromo[1,2,3]-triazolo[1,5-a]pyridine
TLDR
A nucleophilic substitution of 5bromotriazoloisoquinoline (3) and 7-bromo-3-methyltrieazolopyridine (6) proceeds readily to give a range of 5-substituted triazoloenoquinolines (4a)-(4e), and of 7-substantituted trichloropyridines (7a-(7h) respectively.About:
This article is published in Tetrahedron.The article was published on 1988-01-01. It has received 13 citations till now. The article focuses on the topics: Morpholine & Nucleophilic substitution.read more
Citations
More filters
Journal ArticleDOI
Copper-catalyzed tandem synthesis of [1,2,3]triazolo[5,1-a]isoquinolines and their transformation to 1,3-disubstituted isoquinolines
TL;DR: In this article, 2-Azido-3-(2-iodophenyl)acrylates react with terminal alkynes in the presence of a copper(II) catalyst without ligands to give a wide range of [1,2,3]triazolo[5,1-a] isoquinolines in good yields.
Journal ArticleDOI
Deprotonative magnesation and cadmation of [1,2,3]triazolo[1,5-a]pyridines.
Ghenia Bentabed-Ababsa,Fernando Blanco,Aicha Derdour,Florence Mongin,François Trécourt,Guy Queguiner,Rafael Ballesteros,Belen Abarca +7 more
TL;DR: Attempts to obtain the cross-coupling products using 2-bromopyridine under palladium catalysis failed, a result attributed to the low stability of these compounds.
Journal ArticleDOI
Triazolopyridines. 18. Nucleophilic substitution reactions on triazolopyridines; a new route to 2,2′-bipyridines☆
Gurnos Jones,M. A. Pitman,Edward Lunt,David J. Lythgoe,Belén Abarca,Rafael Ballesteros,Mostafá Elmasnaouy +6 more
TL;DR: In this paper, the synthesis of 5-, 6-, and 7-halogenotriazolopyridines is described, and their reactions with nucleophiles are described.
Journal ArticleDOI
The chemistry of [1,2,3]triazolo[1,5-a]pyridines.
TL;DR: The reactivity of [1,2,3]triazolo[1,5- a] pyridine 1 is described and a new way to 2,2′-bipyridines, in two steps from triazolopyridsines is reported.
Journal ArticleDOI
Triazolopyridines. Part 26: The preparation of novel [1,2,3]triazolo[1,5-a]pyridine sulfoxides ☆
Belén Abarca,Rafael Ballesteros,Rafael Ballesteros-Garrido,Rafael Ballesteros-Garrido,Françoise Colobert,Frédéric R. Leroux +5 more
TL;DR: In this paper, the regioselective synthesis of new triazolopyridine halides and sulfoxides with the substituent in all different ring positions of [1,2,3]triazolo[1,5-a ]pyridines is presented.
References
More filters
Journal ArticleDOI
Triazolopyridines. Part 7. Preparation of bromo-triazolopyridines and -triazoloisoquinolines
TL;DR: Bromination of the 7-lithiotriazolopyridines (7) and (10) gave small yields of 7-bromotriazolatemorphine (8), 5-trimethylsilyltriaxoloisoquinoline (5) and its lithium derivative as discussed by the authors.
Journal ArticleDOI
Triazolopyridines. Part 2. Preparation of 7-substituted triazolo[1,5a]pyridines by directed lithiation
Gurnos Jones,D. Robert Sliskovic +1 more
TL;DR: In this paper, the lithiation reactions of 1,2,3-triazolo[1,5-a]pyridine (1) to give the 7-lithio-derivative (4; R = Li), and of its 7-methyl derivative (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 30] to give 6-substituted pyridine-2-carbaldehydes were described.
Journal ArticleDOI
Triazolopyridines. Part 6. Ring opening reactions of triazolopyridines
TL;DR: The triazole ring in 1,2,3-triazolo[1,5-a]-pyridines and -quinolines can be opened with loss of nitrogen.
Journal ArticleDOI
Nucleophilic substitutions on bromotriazolopyridines - an improved route to 2,6-disubstituted pyridines and to 1,3-disubstituted isoquinolines
TL;DR: In this article, a regiospecific synthesis of 2,6-disubstituted pyridines and 1,3-dissubstitized isoquinolines is described.
Journal ArticleDOI
Rearrangements of azabiphenylenes. The impact of nitrogen number and position
TL;DR: A partir des diethynyl-2,3 methoxy-4- ou diethyl-3,4 methoxy 2 pyridine and bis-trimethylsilyl acetylene en presence de complexe de cobalt, synthese des methoxy 4 benzo [3, 4] cyclobuta [1,2-b]pyridine (A) and methoxy 1 benzo cyclobita [3.4]-cyclobuta[1, 2-c]Pyridine(B) as discussed by the authors.