Journal ArticleDOI
Ultracytochemical Localization of Calcium in the Superficial Pineal Gland of the Mongolian Gerbil
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TLDR
The pyroantimonate technique was employed to demonstrate fine localization of Ca2+ in the superficial pineal gland of Meriones unguiculatus and obtained reaction product using an energy‐dispersive x‐ray microanalysis.Abstract:
In order to demonstrate fine localization of Ca2+ in the superficial pineal gland of Meriones unguiculatus, the pyroantimonate technique was employed. Control experiments were performed with EGTA and analysis of obtained reaction product using an energy-dispersive x-ray microanalysis.
Precipitates of calcium antimonate were formed almost exclusively in swollen clear pinealocytes, in and along their cell membranes, over their nuclei, in mitochondria, the Golgi apparatus, endoplasmic and integrade reticulums. acervuli, in vesicles surrounding synaptic bars, cytoplasmic matrix, and flocculent extracellular material. It has been concluded that the swollen pinealocytes represent a degenerative cell form probably occurring by impairment of plasmalemmal Ca2+-ATPase's ability to eliminate Ca2+ ion from the cell, with consecutive increase of calcium in the cytoplasmic matrix, followed by increase of intramitochondrial Ca2+ concentration, gradual arrest of mitochondrial function, depolymerization of cytoskeletal microtubuli, loss of the cell form, and cell death. Decrease of function of pinealocyte plasmalemma seems to be related to aging.read more
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Fluoride Deposition in the Aged Human Pineal Gland
TL;DR: By old age, the pineal gland has readily accumulated F and its F/Ca ratio is higher than bone, and there was a positive correlation between pineal F and pineal Ca but no correlation between tree F and bone F.
Journal ArticleDOI
Comparative histology of pineal calcification
TL;DR: It is concluded that a multifactorial mechanism may be responsible for the calcification of the pineal organ and the formation of these layers is connected to circannual changes in the calcium level of the organ.
Journal ArticleDOI
The Decrease of Pineal Melatonin Production with Age
Willy Humbert,Paul Pévet +1 more
TL;DR: The hypothesis of “loss of circadian rhythmicity in aging” is supported by numerous animal studies and is hypothesized that the gradual and progressive deterioration of functional potential is the result of the loss of coordination among the many interdependent oscillating systems.
Journal ArticleDOI
Morphofunctional aspects of the mammalian pineal gland.
Michal Karasek,Russel J. Reiter +1 more
TL;DR: The primary aim of this review is to present the current state of knowledge of the ultrastructure of the mammalian pineal gland, with emphasis on its functional aspects.
References
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Journal ArticleDOI
Further study of the role of calcium in synaptic transmission
Bernard Katz,Ricardo Miledi +1 more
TL;DR: The effect of calcium on synaptic transmission has been studied by intracellular recording of pre‐ and post‐synaptic potential changes in the stellate ganglion of the squid by using Na6(CO3)(SO4)2, Na2SO4, and Na2CO3 as slurs.
Journal ArticleDOI
Elektronenmikroskopische Lokalisation von Na+ und Cl− in Zellen und Geweben
TL;DR: In this article, the authors present an analysis of the morphologie des Stofffransportes in der Salzdriise (K o m n i e k 1961) and their effect on the performance of the Stoffe in situ.
Journal ArticleDOI
Selective localization of intracellular Ca2+ with potassium antimonate.
Susan M Wick,Peter K. Hepler +1 more
TL;DR: It is hoped that this cxercise provides evidence that it is possible to employ antimonate as a selective electron microscopic histoehemical stain for localization of exchangeable cellular Ca2 and that, in spite of inevitable limitations, it is a useful tool for exploring Ca2 regulation.
Journal ArticleDOI
The subcellular localization of calcium ion in mammalian myocardium
TL;DR: Tissue examined in the electron microscope showed a consistent and reproducible localization of the electron-opaque pyroantimonate salts of sodium and calcium to distinct sites in the tissue, suggesting that subcellular calcium is sequestered in specific sites in mammalian myocardium.
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