Journal ArticleDOI
Understanding dementia: diagnosis and development
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TLDR
The different types of diseases that can lead to dementia symptoms and how these diseases are diagnosed are explained to enable support workers to understand the reasons dementia develops, its stages and how it is diagnosed.Abstract:
Dementia is a term used to describe the symptoms of a range of progressive, terminal, organic brain diseases. It can lead to neuropsychiatric symptoms and behaviours that are considered challenging. This article explains the different types of diseases that can lead to dementia symptoms and how these diseases are diagnosed. It aims to enable support workers to understand the reasons dementia develops, its stages and how it is diagnosed.read more
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Presynaptic nigro-striatal function in a group of Alzheimer's disease patients
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Why didn't I know? Perspectives from adult children of elderly parents with dementia.
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Dementia and the Gap in Nutrition: A Review
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Dementia: prevalence and pathophysiology
TL;DR: The number of people with dementia in the UK is projected to rise to 1.14 million by 2025 and to 2.09 million by 2051, as a result of population ageing, according to the Office for National Statistics.
References
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Journal ArticleDOI
Knowing Where and Getting There: A Human Navigation Network
Eleanor A. Maguire,Neil Burgess,James G. Donnett,Richard S. J. Frackowiak,Chris D. Frith,John O'Keefe +5 more
TL;DR: A network of brain areas that support navigation in humans are outlined and the functions of these regions are linked to physiological observations in other mammals.
Journal ArticleDOI
Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD.
TL;DR: There is considerable promise that early and specific diagnosis is feasible through a combination of imaging modalities, and the value of FDG-PET in diagnosing AD-like changes, particularly at an early stage, and in providing diagnostic specificity is put into perspective.
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Psychiatric morbidity in dementia with Lewy bodies: a prospective clinical and neuropathological comparative study with Alzheimer's disease.
Clive Ballard,Clive Holmes,Ian G. McKeith,David Neill,John T. O'Brien,Nigel J. Cairns,Peter L. Lantos,Elaine K. Perry,Paul G. Ince,Robert H. Perry +9 more
TL;DR: Delusional misidentification and hallucinations in the early stages of dementia may improve differentiation between patients with dementia with Lewy bodies and those with Alzheimer's disease and have important treatment implications.
Journal ArticleDOI
Motor and cognitive function in Lewy body dementia: comparison with Alzheimer's and Parkinson's diseases.
TL;DR: EPS in Lewy body dementia resemble those seen in idiopathic Parkinson's disease, although less rest tremor and left/right asymmetry but more severe rigidity favours a diagnosis of LewyBody dementia.
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Prognosis of Parkinson disease: risk of dementia and mortality: the Rotterdam Study
Lonneke M. L. de Lau,C. Maarten A. Schipper,Albert Hofman,Peter J. Koudstaal,Monique M.B. Breteler +4 more
TL;DR: Especially patients with Parkinson disease who carry an APOE epsilon2 allele have an increased risk of developing dementia and increased mortality risk in Parkinson disease is dependent on disease duration and is only modest in the absence of dementia.