The appearance of this massive work after years of preparation represents a major publishing milestone in pediatrics. It is the stated intent of the editors to relate the basic science aspect of pediatrics to clinical practice, and the book is a natural outgrowth of the expanding, productive basic research in pediatrics. The book is divided into three parts. The first, "Sciences Fundamental to an Understanding of Growth and Maturation," is a pedantically turgid exposition of cell biology, heredity, and the behavioral sciences, too much for a pediatrics book and not enough for a text on cell biology. The second part, "Anatomic and Functional Systems of the Child," forms approximately two thirds of this bulky book. The content corresponds to the standard American textbooks, but the manner of presentation is vastly different. Major emphasis is given to the relation of disease to structure and function, with attention to clinical descriptions. For

Water and electrolyte balance in the normal child.

The Biologic Basis of Pediatric Practice

The biologic basis of pediatric practice

Recent work on the basal metabolism of infants and adults has revived interest in Rubner's law that heat production in different individuals and species of animals is proportional to the surface area. This law was first definitely formulated by Rubner 1 in 1883, although suggested by Bergman 2 many years before. At the time the experimental work in support of this theory was done no record was kept of body movements and men and animals were allowed to move during the periods of investigation. The average heat production per square meter of body surface was about 1,000 calories per day. In modern work, where the influence of muscular activity is absolutely excluded, the figure is in the neighborhood of 830 calories per square meter per day, as has been shown in Paper 4 of this series. With these new figures it is not unnatural that many

Fifth paper the measurement of the surface area of man

background

Fluid and electrolyte composition of the fetus and the newborn.

Total body water and normal electrolyte composition.

Monitoring of the urinary output and urine specific gravity during surgery on an hourly basis has provided a practical guide to fluid therapy in paediatric surgery. During surgery the infusion of a polyionic fluid with a plasma-like composition (lactated Ringer’s solution) proved not to be detrimental to the patients; on the contrary, it resulted in a significant reduction in operative and postoperative morbidity. Blood transfusion became of secondary importance because it was not used to restore blood volume but to replace proteins and red blood cells.

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Water and electrolyte balance in the normal child.

Citations

The Biologic Basis of Pediatric Practice

The biologic basis of pediatric practice

References

Fifth paper the measurement of the surface area of man

The Biologic Basis of Pediatric Practice

Fluid and electrolyte composition of the fetus and the newborn.

Total body water and normal electrolyte composition.

Fluid therapy during paediatric surgery.

Related Papers (5)

On fluid balance

Changes in water and electrolyte balance in pregnancy

Electrolyte and Fluid Balance

Fluid and electrolyte balance in the newborn

Control of body fluid volume.