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Journal ArticleDOI
Intrathyroidal epithelial thymoma : An entity distinct from squamous cell carcinoma of the thyroid
Akira Miyauchi,Kanji Kuma,Fumio Matsuzuka,Sunao Matsubayashi,Akira Kobayashi,Hajime Tamai,Shoichi Katayama +6 more
TL;DR: Thymoma can arise in the thyroid gland presumably from aberrant thymic tissue, mimicking squamous cell carcinoma; and the prognosis of thymoma is favorable; therefore, it is important to discriminate thymom from squamouscell carcinoma of the thyroid, which is usually fatal.
Journal ArticleDOI
Clinicopathologic significance of intrathyroidal epithelial thymoma/carcinoma showing thymus-like differentiation: a collaborative study with Member Institutes of The Japanese Society of Thyroid Surgery.
TL;DR: It is suggested that curative resection followed by radiation therapy may effectively prevent locoregional recurrence and CD5 immunostaining is useful for diagnosing ITET/CASTLE.
Journal ArticleDOI
Intrathyroidal epithelial thymoma (ITET)/carcinoma showing thymus-like differentiation (CASTLE) exhibits CD5 immunoreactivity: new evidence for thymic differentiation
TL;DR: Cases of intrathyroidal epithelial thymoma (ITET)/carcinoma showing thymus‐like differentiation (CASTLE) were examined for CD5 immunoreactivity, a feature of true thymic carcinoma, but not otherThymic epithelial neoplasms or carcinomas of other sites.
Journal ArticleDOI
Intrathyroid epithelial thymoma (ITET) and carcinoma showing thymus-like differentiation (CASTLE): CD5-positive neoplasms mimicking squamous cell carcinoma of the thyroid.
TL;DR: The tumors in 15 cases demonstrate 3 histological subtypes: keratinizing squamous cell carcinoma type, non-keratinizing basaloid cell carcinomas (lymphoepithelioma-like) type and neuroendocrine carcinomas type, which correspond to subtypes of the mediastinal thymic carcinomas.
Journal ArticleDOI
Carcinoma of the neck showing thymic-like elements (CASTLE): report of a case and review of the literature.
Maria Gaia Piacentini,Fabrizio Romano,Sergio De Fina,Paola Sartori,Eugenio Biagio Leone,Barbara Rubino,Franco Uggeri +6 more
TL;DR: By the analysis of the 18 cases reported in literature, total thyroidectomy with selective modified neck dissection should be the treatment of choice and radiotherapy should be considered for patients with positive nodal status.