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Can a virus cause low ejection fraction? 

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Our data suggest that the fraction of viruses attached to TEP is highest in areas characterized by a low renewal rate of the water mass and can constitute at times a significant fraction of total virus abundance.
The activity in the peak fraction seemed to be structually associated with virus particles.
Nor does it depend on the ejection of saliva in itself; for this alone did not reduce the numbers of aphids that transmitted virus.
This study also suggests that metals or metal oxides on sand surfaces can cause significant virus removal under high ionic strength conditions.
Open accessJournal ArticleDOI
Gareth A. Maglennon, John Doorbar 
66 Citations
In addition to immune-mediated latency, it appears that a similar situation can be achieved following infection at low virus titres and/or infection at epithelial sites where the virus life cycle is not properly supported.
However, while ejection fraction is statistically associated with mortality, it is only one of multiple factors that impact on mortality.
The association of mature virus with the large-particle fraction could be explained in part by adsorption of free virus to a component of this fraction; treatment with EDTA released the virus.
Activation of virus appears to be a very low-frequency event.
The dangers of focusing on ejection fraction are that many patients whose ejection fractions exceed commonly used cut offs experience sudden death.
This fraction apparently contains disrupted virus envelopes.
However, the virus may be the cause of serious diseases, particularly in immunocompromised individuals.