Can next-generation vaccine technologies revolutionise helminth vaccinology?
Best insight from top research papers
Next-generation vaccine technologies have the potential to revolutionize helminth vaccinology. These technologies, such as viral vectors, genetic elements, and recombinant techniques, offer novel approaches to developing effective vaccines against complex helminth parasites. By leveraging -omics technologies and metadata, researchers can expedite target discovery for vaccine development. Additionally, advancements in parasite genomics, including de novo reference quality genomes, enable the identification of potential novel targets for vaccine therapies. Understanding the host-parasite relationship and the immunology involved is crucial for developing successful helminth vaccines, as ineffective immune responses could lead to immunopathogenic reactions. With these advancements and a focus on identifying parasite-specific antigens, there are excellent opportunities for the development of potent next-generation vaccines against helminth infections.
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| Papers (5) | Insight |
|---|---|
86 Citations | Next-generation vaccine technologies, combined with understanding host-parasite immunology, offer promising opportunities to revolutionize helminth vaccinology by enhancing efficacy and safety of antihelminth vaccines. |
32 Citations | Next-generation vaccine technologies can revolutionize helminth vaccinology by identifying potential novel targets for vaccine therapies through genomic comparisons of parasitic helminth species. |
Open access•Journal Article 1 Citations | Next-generation vaccine technologies, like recombinant and DNA vaccines, offer promise in revolutionizing helminth vaccinology by providing cost-effective, stable, and potentially more effective solutions compared to traditional methods. |
18 Citations | Next-generation vaccine technologies like viral vectors and genetic elements show promise in revolutionizing helminth vaccinology by offering novel approaches for developing potent vaccine platforms. |
50 Citations | Next-generation vaccine technologies, such as in silico vaccinology and systems biology approaches, have the potential to revolutionize helminth vaccinology by identifying protective antigens and enhancing vaccine development. |
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