CRISPR technology work in treating powdery mildew disease in wheat?
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Yes, CRISPR technology has shown promising results in treating powdery mildew disease in wheat. Studies have identified negative genetic factors related to powdery mildew, such as TaEDR1, which negatively regulates resistance to powdery mildew in wheat . By using CRISPR/Cas9 technology, researchers have successfully generated wheat plants with mutations in genes like TaMLO, leading to broad-spectrum resistance against powdery mildew . Additionally, the knockout of specific gene alleles in wheat has been shown to confer resistance to powdery mildew, highlighting the potential of CRISPR technology in enhancing disease resistance in wheat . These findings demonstrate the effectiveness of CRISPR technology in combating powdery mildew in wheat, offering a valuable approach for disease resistance breeding in this important crop.
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| Papers (5) | Insight |
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1.4K Citations | Yes, CRISPR technology was used to generate mutations in a single TaMLO allele, contributing to heritable resistance to powdery mildew in wheat, as demonstrated in the study. |
| CRISPR technology was used to knockout all six alleles of a gene in wheat, providing resistance to powdery mildew, showcasing its potential in treating the disease. | |
| Yes, CRISPR/Cas9 technology has been utilized to genetically modify wheat for powdery mildew resistance, among other traits, showcasing its effectiveness in improving wheat characteristics. | |
| CRISPR/Cas knockdowns targeting negative regulators (S genes) can enhance genetic resistance against powdery mildew in wheat by disrupting specific genes, as suggested in the reviewed research. | |
| Yes, CRISPR/Cas9 technology was used to simultaneously modify three homoeologs of TaEDR1 in wheat, enhancing powdery mildew resistance without off-target mutations, as demonstrated in the study. |
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