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Does mentzer index differ in different mutations of thalassemia carriers?

Iron-deficiency anemia

Microcytic anemia

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The diagnostic value of the Mentzer Index in differentiating between thalassemia carriers and iron deficiency anemia has been studied in several papers. The Mentzer Index has been found to be reliable in detecting true positive cases for β-thalassemia trait, with a sensitivity of 89.0% and specificity of 87.9% . It has also been demonstrated that the Mentzer Index can separate individuals with β-thalassemia minor from those without, regardless of their iron status . Additionally, the Mentzer Index has been shown to be useful in initiating screening for thalassemia carriers, regardless of iron status, in low resource settings . However, there is no specific mention of the Mentzer Index differing in different mutations of thalassemia carriers in the abstracts provided.

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Open access Indeks RDW dan Mentzer sebagai Uji Skrining Diagnosis Thalassemia Rembulan Ayu Np 01 Jun 2015 2 Citations	The paper does not provide information on whether the Mentzer index differs in different mutations of thalassemia carriers.
Journal Article•DOI Screening For Thalassemia Carriers In Populations With High Rate Of Iron Deficiency: Revisiting The Applicability Of Mentzer Index and The Effect Of Iron Deficiency On HbA2 Level Ali Amid, Bahram Haghi Ashtiani, Mohammad Taghi Haghi Ashtiani - Show less +2 more 15 Nov 2013-Blood 2 Citations	The paper does not mention anything about the different mutations of thalassemia carriers and their impact on the Mentzer Index.
Journal Article•DOI Screening for Thalassemia Carriers in Populations with a High Rate of Iron Deficiency: Revisiting the Applicability of the Mentzer Index and the Effect of Iron Deficiency on Hb A2 Levels Ali Amid, Bahram Haghi-Ashtiani, Melanie Kirby-Allen, Mohammad Taghi Haghi-Ashtiani - Show less +3 more 17 Apr 2015-Hemoglobin 8 Citations	The study does not provide information on whether the Mentzer Index differs in different mutations of thalassemia carriers.
Open access•Journal Article•DOI Evaluation of the diagnostic reliability of Mentzer index for Beta thalassemia trait followed by HPLC Shubhi Saxena, Richa Jain - Show less +1 more 20 Feb 2020 2 Citations	The given information does not provide any details about the different mutations of thalassemia carriers and their impact on the Mentzer index.
Open access•Journal Article•DOI Mentzer Index Diagnostic Value in Predicting Thalassemia Diagnosis Wahyu Siswandari, Lantip Rujito, Vitasari Indriani, Wahyu Djatmiko - Show less +3 more 01 Apr 2019 4 Citations	The paper does not provide information on whether the Mentzer Index differs in different mutations of thalassemia carriers.

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