Does the SWI/SNF complex activate or repress transcription?
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The SWI/SNF complex can both activate and repress transcription. It plays a crucial role in gene regulation and chromatin remodeling . The complex is involved in the activation of late inflammatory genes in response to microbial challenge . It also promotes homologous recombination and is recruited to double-strand breaks in a transcription-dependent manner . Additionally, the SWI/SNF complex is implicated in DNA repair, replication, and accessibility for selective gene transcription . The complex can be dynamically regulated in response to environmental cues, such as hypoxia . Overall, the SWI/SNF complex has diverse functions in transcriptional regulation, DNA repair, and chromatin remodeling, highlighting its importance in various biological processes.
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12 Dec 2022 | The paper does not explicitly state whether the SWI/SNF complex activates or represses transcription. |
| The paper does not explicitly state whether the SWI/SNF complex activates or represses transcription. | |
1 Citations | The paper does not explicitly state whether the SWI/SNF complex activates or represses transcription. |
| The SWI/SNF complex is involved in both activating and repressing transcription, as different subunits of the complex have distinct roles in promoting transcriptional silencing and maintaining it. | |
| The SWI/SNF complex is involved in the activation of transcription, as it regulates chromatin accessibility and enhances the transcriptional activation ability of the BZR1 transcription factor. |
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