Hepatoprotective druge for hepatitis a?
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Hepatoprotective drugs for hepatitis A include various agents with proven efficacy in reducing liver damage. Studies have shown that hepatoprotectors like remaxol, ademetionine, ursodeoxycholic acid, Laennec, and 3-(4-bromophenyl)-6,6-dihydroxy-5-hydroxyiminohexahydro-2,4-pyrimidinedione can be beneficial. These drugs exhibit antioxidant effects, reduce hepatocyte cytolysis, and protect against inflammatory responses, oxidative stress, and apoptosis. Ademetionine, in particular, has been highlighted for its choleretic, cholekinetic, regenerating, antioxidant, and antitoxic properties, making it a valuable option for managing drug-induced liver injury. Therefore, a combination of these hepatoprotective agents can be considered for treating hepatitis A, providing comprehensive protection and support for liver function.
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| Not addressed in the paper. | |
| Remaxol, ademetionine, and ursodeoxycholic acid are hepatoprotective drugs studied for alcoholic hepatitis, showing comparable efficacy in reducing hepatocyte cytolysis and oxidative stress markers in patients' blood. | |
| 4-Octyl Itaconate (OI) demonstrates hepatoprotective effects in autoimmune hepatitis, reducing inflammation, oxidative stress, and hepatocyte death by activating Nrf2 and inhibiting NF-𝜅B signaling pathways. | |
05 Oct 2022 | The drug Laennec, derived from human placental hydrolysates, exhibits hepatoprotective effects in toxic liver injury induced by alcohol or paracetamol, reducing liver dysfunction markers and preserving liver parenchyma. |
| The drug with hepatoprotective activity mentioned in the paper can be effective for treating liver diseases like hepatitis, potentially offering hepatoprotection in combination with other preparations. |
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