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How does the choice of kidney substitution therapy (dialysis vs transplant) impact the clinical outcomes of intoxicated patients? 


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The choice of kidney substitution therapy, whether dialysis or transplant, significantly impacts the clinical outcomes of intoxicated patients. Studies have shown that kidney transplantation is considered the best renal replacement therapy, offering better survival rates compared to dialysis . Patients transitioning from hemodialysis to peritoneal dialysis have shown improved outcomes, including reduced mortality and increased access to transplantation . Additionally, the combination of hemodialysis with conventional treatment and naloxone has been found to reduce hospital stay, coma time, and overall complication rates in patients with acute severe alcohol intoxication . However, the decision to opt for kidney transplantation may be influenced by factors such as lack of information, age, contraindications, and perceptions of outcomes . Ultimately, the choice between dialysis and transplant plays a crucial role in determining the clinical outcomes of intoxicated patients.

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