How does the molecular weight of chitosan impact the phase structure of calcium phosphate during precipitation?
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The molecular weight of chitosan influences the phase structure of calcium phosphate during precipitation. Higher molecular weight chitosan tends to impact the morphology and composition of the precipitated calcium phosphate differently compared to lower molecular weight chitosan. Studies have shown that medium molecular weight chitosan, when combined with amino acids like glutamic or aspartic acid, can lead to the synthesis of calcium hydrogen phosphate dihydrate and amorphous calcium phosphate, with the specific amino acid affecting the morphology of the phases formed . Additionally, the degree of deacetylation (DDA) of chitosan plays a role in the composition, structure, and crystallinity of calcium phosphate coatings, with higher DDA chitosan resulting in more crystalline calcium phosphate structures . Therefore, the molecular weight of chitosan is a critical factor in determining the phase structure of calcium phosphate during precipitation.
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Open access 01 Jan 2013 | The molecular weight of chitosan influences the crystallization of calcium phosphate particles, with chitosan playing a controlling role in the growth of the crystals within the nanocomposite. |
45 Citations | The degree of deacetylation (DDA) of chitosan, not its molecular weight, influences the phase structure of calcium phosphate during precipitation on chitosan films. |
1 Citations | The medium molecular weight chitosan influences the phase structure of calcium phosphates during precipitation, with the presence of glutamic or aspartic acid affecting the morphology of the phases formed. |
| Chitosan's molecular weight affects calcium phosphate phase structure during precipitation. Higher molecular weight chitosan inhibits amorphous calcium phosphate transformation, influencing the crystalline phase composition and morphology. | |
| The molecular weight of chitosan affects the phase structure of calcium phosphate layers, influencing physico-chemical properties and adherence strength, as observed in the composite layers synthesized in the study. |
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