How long does a neuron cell in a human live on average?
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Comparison with the pattern of neuron death in human AD suggests that each may represent a distinctly different disease model when used in preclinical trials. | |
307 Citations | Experimental studies show the dependence that a neuron has on the cell population with which it ultimately connects. |
The evidence to date is compatible with the requirement for a second "hit" for a neuron to progress cell cycle initiation and DNA replication to death. | |
This finding could be relevant in cell replacement studies with animal models featuring spiral ganglion neuron degeneration. |
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