How many genes in human have a kinase motif?
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The human genome contains 518 genes that have a kinase motif . These genes are involved in various physiological functions and are also implicated in diseases . The kinases play a significant role in cellular processes such as proliferation, maintenance of cell shape, and apoptosis . A comprehensive computational analysis of naturally occurring single nucleotide polymorphisms (SNPs) in kinases revealed that the kinase catalytic domain and receptor structures are enriched with disease-causing variations . The analysis also identified 106 protein kinase pseudogenes and mapped 244 kinases to disease loci or cancer amplicons . Additionally, a structure-based sequence alignment of 497 human protein kinase domains identified conserved regions and functional motifs, providing insights into the functions and phenotypes of kinases .
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| The paper does not provide the exact number of genes in humans that have a kinase motif. | |
| The paper states that there are 518 putative protein kinase genes in the human genome. | |
27 Citations | The paper does not provide the exact number of genes in humans that have a kinase motif. |
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