How much energy does it take to fire a neuron?
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| Papers (8) | Insight |
|---|---|
| Our results suggest that the mean firing rate (frequency) of periodically spiking neuron does not carry any information other than identifying a channel of communication. | |
638 Citations | It seems probable that the supply of energy may impose a limit on the activity of a neuron under normal conditions. |
14 Jun 2014 12 Citations | Together, these simplifications yield two stage neuron behavior with energy efficiency that is only about a factor of two worse than the simplest one stage neuron. |
43 Citations | The delayed response of Hamilton energy to external forcing currents confirms that neuron contributes to energy coding. |
21 Citations | These theoretical calculations also prompt an assumption that there may be a considerable difference between oxygen consumption and neuron energy levels. |
| It can be used for investigation about the energy coding in the neuron even the neuron networks. | |
09 Jun 2019 41 Citations | This work provides a highly-integrated and inherently-low-energy implementation for neuron and the possibility for all-ferroelectric neural networks. |
| Overall this work illustrates how a hardware-realisable neuron model can capitalise on the unique computational capabilities of biological neurons. |
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Can N2A cells fire action potential ?5 answersN2A cells, when transfected with tau plasmids, show a downregulation of mRNA levels of several Kv channels, including Kv2.1, Kv3.1, Kv4.1, Kv9.2, and KCNH4, and a reduction in macroscopic currents through Kv channels, indicating an impact on electrical activity. On the other hand, NT2 neurons (NT2Ns) derived from stem cells exhibit sodium-dependent action potentials and responses to depolarization and neurotransmitters, showcasing their ability to generate action potentials. Additionally, exposure to 17β-estradiol inhibits Kv currents in N2A cells in a concentration-dependent manner, affecting peak and steady-state currents through Kv channels, suggesting a modulation of electrical activity. Therefore, while N2A cells can exhibit changes in Kv channel activity under certain conditions, stem cell-derived neurons like NT2Ns are capable of firing action potentials.
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