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How would clumping in palettes affect the quality control of plasma blood bags?

Volume (thermodynamics)

Fresh frozen plasma

Hydrogen peroxide

Quality (philosophy)

Blood Component Removal

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Clumping in platelets can impact the quality control of plasma blood bags by potentially leading to issues during transfusion processes. Platelet clumps can interfere with the preparation and storage of blood components, affecting the overall quality of the product. Additionally, clots within the blood bag or transfusion set can obstruct flow, causing complications during transfusion. Quality control measures for fresh frozen plasma (FFP) include checking for residual cells, volume, and pH, where deviations from standards can indicate quality issues. Proper preparation of fresh frozen plasma is crucial to maintain coagulation factors and inhibitors at normal levels, ensuring quality for transfusion purposes. Therefore, clumping in platelets can disrupt the quality control process of plasma blood bags, potentially affecting the safety and efficacy of transfusions.

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Journal Article•DOI Reproducible delayed appearance of platelet clumps and acanthocytes in blood components collected from a single donor Shinji Oikawa, Shoichi Ito, Chihiro Odajima, Yasuhito Horibe, Shinichi Urano, Ko Suzuki, Masayoshi Minegishi, Takashi Itoh, Itaru Shibasaki, Hiroshi Shimizu - Show less +9 more 01 Feb 2016-Transfusion Medicine	Clumping in platelets can impact the quality control of plasma blood bags by potentially rendering the product unusable due to the presence of abnormal morphology and clumps.
Journal Article•DOI A rare cause of blood clots in blood bag. N. Bejarano, J. Macías, C. Sanz, A. Pereira - Show less +3 more 01 Feb 2017-Transfusion Medicine 1 Citations	Clumping in palettes can indicate bacterial growth in blood components, affecting quality control. Inspection for clots before transfusion is crucial to prevent potential risks.
Open access•Journal Article•DOI Retracted: Research on the Factors Damaging Hydrogen Peroxide Low-Temperature Plasma Sterile Packaging Bags and the Control of Link Quality Evidence-Based Complementary and Alternative Medicine 21 Jun 2023-Evidence-based Complementary and Alternative Medicine	Not addressed in the paper.
Open access•Journal Article•DOI Quality Control of Fresh Frozen Plasma in Hospital Blood Bank Using pH, Volume, Residual Cells Count, PT, and PTT Abdel Rahim Muddathir 30 Oct 2022-Egyptian Academic Journal of Biological Sciences. C, Physiology & Molecular Biology	Clumping in platelets can impact the quality control of plasma blood bags by potentially affecting platelet count accuracy, leading to deviations from international standards in transfusion readiness.

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