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Is caffeic acid safe in skincare? 


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Caffeic acid has been extensively studied for its safety and efficacy in skincare products. Research indicates that caffeic acid, known for its antioxidant properties, can be safely incorporated into skincare formulations. Studies have shown that caffeic acid does not exhibit cytotoxic effects on skin cells at concentrations commonly used in skincare products. Furthermore, the use of caffeic acid in skincare has been associated with benefits such as increased collagen production, prevention of premature aging, and antioxidant activity. The compound has also been found to enhance the photoprotective properties of sunscreens, making it a valuable addition to such formulations. Overall, the data suggests that caffeic acid is safe for use in skincare products and can offer various skin benefits.

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Papers (5)Insight
Caffeic acid, a type of chlorogenic acid found in coffee, is safe in skincare due to its antioxidant, anti-aging, and photoprotective properties, as highlighted in the paper.
Caffeic acid is safe for skincare as it did not exhibit toxicity in HepG2 and HaCat cells at concentrations needed for antioxidant activity in vitro.
Caffeic acid in skincare formulations, such as films and emulsions, shows promise with high skin retention, indicating safety and potential efficacy for dermatological use.
Caffeine, not caffeic acid, is safe in skincare. It enhances sunscreen efficacy without causing skin irritation, making it a beneficial adjuvant in dermocosmetics.
Both solid lipid nanoparticles and ethosomes loaded with caffeic acid were found to be safe for skin application in an irritation patch test on 20 human volunteers.

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