Is cranberry extract effective in preventing urinary tract infections?
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Cranberry extract has shown effectiveness in preventing urinary tract infections (UTIs) . Studies have demonstrated that cranberry products, containing proanthocyanidins (PACs), can inhibit the adherence of Escherichia coli (E. coli) to the urothelial cells lining the bladder, reducing the risk of UTIs . Cranberry products have been found to be beneficial in reducing the risk of symptomatic, culture-verified UTIs in women with recurrent UTIs, in children, and in people susceptible to UTIs following interventions . However, the evidence currently available does not support the use of cranberry products in the elderly, patients with bladder emptying problems, or pregnant women . Cranberry extracts have also been shown to stimulate the secretion of Tamm-Horsfall Protein (THP), which can bind to UPEC and prevent interaction with host cells, providing a new strategy for UTI prevention . Overall, cranberry extract has demonstrated effectiveness in preventing UTIs, particularly in specific populations, but further research is needed to fully understand its efficacy and potential limitations .
Answers from top 4 papers
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| Papers (4) | Insight |
|---|---|
| Yes, cranberry products, including juice or capsules, have been found to reduce the risk of symptomatic, confirmed urinary tract infections (UTIs) according to the provided paper. | |
| The paper mentions that cranberry extracts have been shown to exert antiadhesive activity against UPEC by stimulating THP secretion, which can prevent urinary tract infections. Therefore, cranberry extract may be effective in preventing UTIs. | |
| The paper discusses the beneficial effects of cranberry extracts in the treatment of urinary tract infections due to their anti-adhesive properties towards bacteria. However, it does not explicitly state whether cranberry extract is effective in preventing UTIs. | |
| Yes, cranberry products are effective in preventing urinary tract infections in women with recurrent UTIs, children, and people susceptible to UTIs following interventions. However, there is no evidence to support its use in the elderly, patients with bladder emptying problems, or pregnant women. |
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