Is protein interaction network adaptive complex system?
Best insight from top research papers
Protein interaction networks are considered adaptive complex systems . The network analysis has contributed to understanding cellular organization in the field of system biology . The alignment of protein interaction networks from different species helps in identifying orthologous proteins, predicting unknown functions, and constructing evolutionary relationships . The complexity of the alignment problem has been addressed by developing scalable algorithms . The molecular architecture underlying complex cellular phenotypes can be investigated using protein interaction network data . These networks provide insights into evolutionary processes and can be analyzed from an evolutionary perspective . Protein-protein interaction networks have been reconstructed for various species and have been used for function annotation, subsystem investigation, evolution analysis, hub protein analysis, and regulation mechanism analysis . Overall, protein interaction networks are adaptive complex systems that play a crucial role in understanding biological processes .
Answers from top 5 papers
More filters
| Papers (5) | Insight |
|---|---|
| The paper does not directly mention whether the protein interaction network is an adaptive complex system. The word "adaptive" is not used in the paper. | |
61 Citations | The paper does not directly answer the question of whether protein interaction networks are adaptive complex systems. The paper discusses the evolutionary analysis of protein interaction networks but does not explicitly address their adaptiveness or complexity. |
| The paper does not directly mention whether protein interaction networks are adaptive complex systems. | |
Open access 01 Jan 2019 | The paper does not explicitly mention whether protein interaction networks are adaptive complex systems. |
Open access•Dissertation 28 Feb 2013 | The paper does not explicitly mention whether the protein interaction network is an adaptive complex system. |
Related Questions
How HOPS complex interacts with different proteins?5 answersThe HOPS (homotypic fusion and protein sorting) complex interacts with various proteins to regulate membrane fusion processes. HOPS has been shown to tether highly curved membranes through direct protein-membrane interactions, particularly via the Vps41p ALPS motif, facilitating vacuole-vacuole contact. Additionally, HOPS interacts with Syntaxin 17 (STX17) to promote autophagosome-lysosome fusion, involving components like VPS33A and VPS16. In Drosophila, all six HOPS subunits are crucial for autophagosome-lysosome fusion, interacting with Syntaxin 17 and ensuring proper trafficking to lysosomes. Moreover, the HOPS complex binds to the vacuolar SNARE complex and specific domains of SNARE proteins, controlling membrane fusion events. Furthermore, HOPS interacts with ERM proteins to facilitate the delivery of cargo like the EGF receptor to lysosomes, regulating endosomal maturation processes.
What are the papers on complex adaptive systems in teacher education?5 answersPapers on complex adaptive systems in teacher education include those focusing on strategies for innovating educational systems through teachers' professional development, the application of an adaptive edusystem to support adaptive teaching and learning in educational settings, and the efficacy of a professional development framework based on complex systems design principles to enhance teacher and student understanding of computational modeling tools. These papers emphasize the importance of adapting teaching methods to suit diverse student needs, promoting systemic developments in educational systems, and utilizing feedback and adaptation principles to improve teacher competences and sustain innovations in real-world educational settings. Additionally, the papers discuss the significance of disrupting the status quo, decentralizing authority, building relational trust, and considering both short-term and long-term goals in educational change and professional development.
How is the current situation of complex adaptive system in education field?5 answersThe current situation of complex adaptive systems in the education field is characterized by the recognition of the need for individualized approaches to learning. Traditional teaching methods that do not take into account the unique characteristics of students are seen as ineffective. The concept of adaptive education has emerged as a way to address this issue, with adaptive teaching and learning models being developed. These models aim to tailor instruction and content to the specific needs of learners, optimizing the learning process. The development of adaptive educational systems is seen as a way to improve the current situation in education, providing adaptive teaching and learning experiences for students. However, it is important to note that while adaptive systems have potential, they are not a panacea for all the challenges faced by the education system.
What is complex adaptive system?4 answersA complex adaptive system is a system that behaves in complex ways due to the interactions between its components and is adaptive to changes in its environment. It is characterized by nonlinearity, dynamism, and emergence. Complex adaptive systems can be applied at different levels, such as individual, team, or organization, and focus on the process of adaptation. They involve concepts such as agents, schemata, fitness functions, resources, agent interactions, and agent tags. These systems are often autonomous and consist of distributed agents that communicate and coordinate their actions through messages. They sense their environments through sensors and act intelligently using actuators, making decisions based on their goals and dynamically changing environment. The study of complex adaptive systems involves understanding the interplay between microscopic processes and macroscopic patterns, as well as the evolutionary forces that shape the systems.
What is protein protein interaction?5 answersProtein-protein interaction (PPI) refers to the physical interaction between two or more proteins. PPIs are essential for various biological functions, including catalysis, regulation, immune response, and inhibition. These interactions play a crucial role in cellular processes such as gene expression, DNA replication, signal transduction, and metabolism. PPIs are driven by a combination of physical and chemical features, including interface residues, hydrophobic effects, hydrogen bonds, and electrostatics, which contribute to the formation of a stable interface for specific molecular function. Understanding PPIs is important for deciphering molecular biology events and can help in the development of new drugs and therapies. Experimental methods such as yeast two-hybrid and biophysical techniques have been used to study PPIs, but computer-aided tools are also being developed for the analysis and prediction of PPIs.
What is adaptability of a complex system?5 answersAdaptability of a complex system refers to its ability to adjust and respond to changes in its environment or requirements. It is a dynamic feature that is present in various domains such as nature, socio-economics, technology, and ecosystems. In the context of designing cyber-physical or manufactured systems, adaptability involves maintaining the original goals of the system while accommodating ongoing changes and avoiding unbounded margins that can be costly. In the field of life sciences, adaptability of complex systems increases behavior uncertainty and poses challenges for precise identification and control, but it can also be seen as a valuable tool for dealing with the complexity of life more effectively. A hierarchical approach is often used to model adaptability, with structural and behavioral levels that impose constraints and allow for system adaptation.