Is there any association between chikungunya and myelitis or any other spinal cord disease?
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Chikungunya fever has been associated with myelitis and other spinal cord diseases. Multiple cases of Chikungunya fever complicated with extensive myelitis have been reported, with spinal cord magnetic resonance imaging (MRI) showing hyperintense lesions in the peripheral regions of the spinal cord . In endemic areas, Chikungunya virus (CHIKV) has been identified as a cause of central nervous system (CNS) infection, including meningoencephalitis and myelitis . Longitudinally extensive transverse myelitis (LETM) has also been rarely associated with CHIKV fever, with only a few reported cases worldwide . Additionally, a mouse model study demonstrated that CHIKV can infect the central nervous system, resulting in encephalitis, myelitis, and peripheral neuropathy . Therefore, there is an association between Chikungunya and myelitis, as well as other spinal cord diseases.
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| Papers (5) | Insight |
|---|---|
| Yes, the paper mentions that chikungunya coinfection can cause transverse myelitis, a spinal cord disease. | |
| The paper does not specifically mention an association between chikungunya and myelitis or any other spinal cord disease. | |
| The paper states that Chikungunya virus (CHIKV) can be associated with neurological complications, including longitudinally extensive transverse myelitis (LETM). | |
| The paper does not specifically mention any association between chikungunya and myelitis or other spinal cord diseases. The paper focuses on the association between chikungunya and neurological manifestations such as meningoencephalitis. | |
8 Citations | Yes, there is an association between Chikungunya and myelitis, as mentioned in the paper "Clinical and magnetic resonance imaging patterns of extensive Chikungunya virus–associated myelitis." |
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