Isolation of iridoids from nyctanthes using column chromatography
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Isolation of iridoids from Nyctanthes arbor-tristis using column chromatography has been a subject of interest due to the plant's pharmacological potential. Traditional chromatographic methods like thin-layer and column chromatography are time-consuming and require large amounts of solvents . Studies have reported the isolation of iridoid glucosides, including rengyolone, 6-O-trans-cinnamoyl-7-O-acetyl-6b-hydroxyloganin, arborside C, 6beta-hydroxy-loganin, and nyctanthoside, from Nyctanthes arbor-tristis flowers using activity-guided fractionation . These iridoid glucosides have shown various biological activities, such as antiplasmodial and antileishmanial properties . The use of column chromatography in isolating iridoids from Nyctanthes arbor-tristis can aid in obtaining pure compounds for further pharmacological studies, potentially enhancing their therapeutic applications.
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11 Citations | Not addressed in the paper. |
103 Citations | Yes, iridoid glucosides (arbortristosides A, B, C, and 6beta-hydroxy-loganin) were isolated from Nyctanthes arbortristis, showing leishmanicidal activity, utilizing column chromatography. |
Open access 01 Jan 2003 | Yes, iridoids were isolated from Nyctanthes arbor-tristis flowers using activity-guided fractionation and column chromatography, leading to the discovery of antiplasmodial compounds like rengyolone and others. |
| Isolation of iridoids from Nyctanthes using column chromatography is time-consuming and requires large amounts of organic solvents, resulting in lower recovery and higher isolation costs. | |
| Column chromatography was utilized for isolating Arbortristoside-C, an iridoid, from Nyctanthes arbor-tristis Linn., as mentioned in the research paper. |
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