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Other than polynucleotide kinase/phosphatase are there any other reported DNA 3'-phosphatases?

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Yes, besides polynucleotide kinase/phosphatase (PNKP), other DNA 3'-phosphatases have been reported. One such enzyme is NExo from Neisseria meningitidis, specialized in removing 3'-phosphate and other 3'-lesions to facilitate DNA repair . Additionally, a label-free hairpin fluorescent biosensor has been developed for the assay of DNA 3'-phosphatases, detecting the activity of T4 polynucleotide kinase phosphatase (PNKP) and shrimp alkaline phosphatase (SAP) with high sensitivity and selectivity . These findings highlight the diversity of DNA 3'-phosphatases beyond PNKP, showcasing the importance of these enzymes in maintaining genomic integrity and DNA repair processes.

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Journal Article•DOI A graphene oxide platform for the assay of DNA 3′-phosphatases and their inhibitors based on hairpin primer and polymerase elongation Wenping Zhu, Ziwei Zhao, Zhen Li, Jian-Hui Jiang, Guo-Li Shen, Ru-Qin Yu - Show less +5 more 21 Jan 2013-Journal of Materials Chemistry B 27 Citations	Not addressed in the paper.
Open access•Journal Article•DOI Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis. Jan Silhan, Qiyuan Zhao, Evzen Boura, Hellen Thomson, Andreas Förster, Christoph M. Tang, Paul S. Freemont, Geoff S. Baldwin - Show less +7 more 14 Dec 2018-Nucleic Acids Research 4 Citations	Yes, NExo from Neisseria meningitidis is a reported DNA 3'-phosphatase specialized in recognizing and repairing the 3'-phosphate lesion, distinct from polynucleotide kinase/phosphatase.
Open access•Journal Article•DOI The polynucleotide kinase 3′-phosphatase gene ( PNKP ) is involved in Charcot-Marie-Tooth disease (CMT2B2) previously related to MED25 Alejandro Leal, Sixto Bogantes-Ledezma, Arif B. Ekici, Steffen Uebe, Christian Thiel, Heinrich Sticht, Martin Berghoff, Corinna Berghoff, Bernal Morera, Michael Meisterernst, André Reis - Show less +10 more 24 Jul 2018-Neurogenetics 33 Citations	Not addressed in the paper.
Open access•Journal Article•DOI DNA Oligonucleotide 3′-Phosphorylation by a DNA Enzyme Alison J. Camden, Shannon M. Walsh, Sarah H. Suk, Scott K. Silverman - Show less +3 more 26 Apr 2016-Biochemistry 24 Citations	Not addressed in the paper.
Open access•Posted Content•DOI Site-specific acetylation of polynucleotide kinase 3’-phosphatase (PNKP) regulates its distinct role in DNA repair pathways Azharul Islam, Anirban Chakraborty, Altaf H. Sarker, Uma K. Aryal, Gulshan Sharma, Istvan Boldogh, Tapas K. Hazra - Show less +6 more 22 Jun 2023-bioRxiv	Not addressed in the paper.

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