Jian-Hui Jiang

TL;DR: A highly sensitive and specific fluorescence resonance energy transfer (FRET) aptasensor for thrombin detection is developed based on the dye labeled aptamer assembled graphene, which exhibits extraordinarily high sensitivity and excellent specificity in both buffer and blood serum.

TL;DR: This Review summarizes the existing fluorescent probes that target chemical/biological events within a single organelle and organelle-anchoring strategies are described and emphasized to inspire the design of new generations of fluorescent probes, before concluding with future prospects on the possible further development of chemical biology.

TL;DR: This research presents a novel probabilistic approach to genome-based approaches to personalized medicine that exploits the “cell reprograming” mechanism to characterize the immune system through “disease-fighting” cells.

TL;DR: It is shown that MWPLSR provides a viable approach to eliminate the extra variability generated by non-composition-related factors such as the perturbations in experimental conditions and physical properties of samples.

TL;DR: WS2 nanosheet can exhibit differential affinity toward short oligonucleotide fragment versus ssDNA probe and act as an efficient quencher for adsorbed fluorescent probes and indicates that this simple and cost-effective strategy holds great potential application in biomedical research and clinical diagnostics.