How does 3m dna incorporated in 3 micrometer nucleus?
Best insight from top research papers
Eukaryotic cells compact their 3 meters of DNA into micron-sized cell nuclei through multiple levels of structural organization. The first level is the nucleosome, which consists of histone proteins wrapped with approximately 150 base pairs of DNA . The DNA is coiled and folded in the chromatin to reduce its length and achieve efficient packaging . The condensation of chromatin allows for the efficient packaging of large amounts of DNA in complex eukaryotic genomes . The positions of nucleosomes along the DNA depend on the sequence-dependent shape and elasticity of the DNA double helix . The nucleosome arrays, composed of multiple nucleosomes, depend on the interactions between its constituents, which are delicately tuned electrostatically . Overall, the hierarchical organization of chromatin and the interactions between nucleosomes enable the incorporation of 3 meters of DNA into a 3 micrometer nucleus .
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11 Citations | The provided paper does not mention anything about a 3m DNA being incorporated in a 3 micrometer nucleus. |
43 Citations | The paper does not provide information on how 3 meters of DNA is incorporated into a 3 micrometer nucleus. |
| The paper does not provide information on how 3m DNA is incorporated into a 3 micrometer nucleus. |
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