Solid state foaming process PCL possible?
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The solid-state foaming process of Poly(e-caprolactone) (PCL) is indeed feasible and has been extensively studied in various research papers. Studies have shown that utilizing supercritical carbon dioxide (scCO2) as a physical blowing agent enables the successful foaming of PCL. The incorporation of other materials such as Poly (lactic-co-glycolic acid) (PLGA), hydroxyapatite, nanocellulose, carboxymethylcellulose, and graphene oxide has been explored to enhance the properties of the foamed PCL structures. Optimal process parameters have been identified, including pressure, temperature, and time, to achieve structures suitable for biomedical applications. The biocompatibility of the resulting PCL foams has been confirmed, making them suitable for use in artificial scaffolds for cell culture in biomedical engineering.
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| Papers (4) | Insight |
|---|---|
| Yes, the paper explores a clean and sustainable method for solid-state foaming of PCL using supercritical CO2/ethyl lactate mixtures, demonstrating the feasibility of this process for PCL foams. | |
| Yes, the paper discusses the foaming of PCL-based composites using supercritical carbon dioxide, demonstrating the feasibility of a solid-state foaming process for PCL in biomedical applications. | |
9 Citations | Solid-state foaming of PCL is possible using supercritical CO2 as a blowing agent, with improved properties by incorporating PLGA in the blend. |
| The research paper explores the feasibility of solid state foaming of PCL-based composites using supercritical carbon dioxide, demonstrating its potential for creating porous structures with tailored properties. |
Related Questions
Solid state foaming process pure PCL at -70degree possible?5 answersSolid-state foaming of pure PCL at -70 degrees Celsius is not feasible based on the data from the provided contexts. The optimal conditions for foaming PCL-based composites using supercritical CO2 were found to be at a temperature of 70 degrees Celsius. Additionally, studies on PCL foaming with supercritical CO2 and ethyl lactate as blowing agents were conducted at temperatures ranging from 35 to 40 degrees Celsius. Furthermore, investigations into the foaming behavior of PCL with nitrogen as the foaming agent did not mention temperatures as low as -70 degrees Celsius, emphasizing the correlation between foaming temperature and foam structure. Therefore, based on the available data, solid-state foaming of pure PCL at -70 degrees Celsius is not supported by the research findings.
Pure PCL can be foaming with external oil or water bath?5 answersPure PCL can be foamed using supercritical carbon dioxide (scCO2) as a foaming agent, as demonstrated in various studies. When scCO2 was utilized as a dispersion medium for nanocomposite preparation and as a blowing agent, poor clay dispersion and non-uniform porous structures were observed. Additionally, the presence of clay in PCL nanocomposites resulted in increased cell density and reduced cell size during the foaming process, attributed to the higher viscosity of the melt. Furthermore, the foaming of PCL-based composites using supercritical carbon dioxide was analyzed, showing significant influence of process conditions on the properties of solid foams, with optimal parameters determined for specific applications. Therefore, external oil or water baths are not necessary for foaming pure PCL, as supercritical carbon dioxide can effectively serve as a foaming agent.
Maximum co2 solubility of PCL in solid state gas absorption?5 answersThe maximum CO2 solubility of polycaprolactone (PCL) in solid-state gas absorption is influenced by various factors such as temperature, pressure, and the specific solvent used. Experimental data suggests that at temperatures ranging from 313 K to 473 K and pressures up to 20 MPa, CO2 solubility in PCL follows Henry's law, with the perturbed-chain statistical associating fluid theory (PC-SAFT) providing accurate correlations for solubility measurements. Additionally, the solubility of CO2 in PCL was found to be influenced by the type of solvent used, with n-hexane showing a more pronounced anti-solvent effect compared to other nonsolvents, leading to a broader heterogeneous region in the solubility curve. These findings highlight the importance of understanding the solubility and diffusivity of CO2 in PCL for designing efficient manufacturing processes.
How does the foam preparation device work?5 answersThe foam preparation device works by combining a foam premixed liquid and gas in a rotating centrifugal system. The device consists of a double-layer rotating cylinder with blades on the inner surface. The foam premixed liquid and gas are introduced through separate inlets in the rotating cylinder. As the cylinder rotates, the blades mix the foam premixed liquid and gas, creating a foam mixture. The foam mixture is then expelled through a foam outlet. The rotation of the cylinder is driven by a gear motor connected to a driving gear and a driven gear on the rotating cylinder. This rotation ensures thorough mixing of the foam premixed liquid and gas, resulting in an improved foam technology for engineering applications.
What kinde of foam produkions exist ?5 answersThere are various foam production methods available. These include batch foaming, extrusion foaming, injection foam moulding, thermoset reactive foaming, compression foam moulding, rotational foam moulding, bead foaming, film foaming. New advanced technologies like microfluidics have also been introduced for the fabrication of foams, allowing for design customization of both liquid and solid foams. Another method involves mixing liquid nitrogen with a foaming material to produce foam, which can be used in fire extinguishing. Additionally, foams can be produced by reacting polyisocyanate and waterglass without the use of a blowing agent, with foaming achieved by the controlled release of CO2. Carbon foams can be produced using carbon fibers, with a specific fiber diameter range.
Why use PCL for "bone tissue engineering"?1 answersPolycaprolactone (PCL) is widely used in bone tissue engineering due to its advantages such as good biocompatibility, slow degradation rate, and potential for load-bearing applications. PCL can be easily processed into three-dimensional (3D) scaffolds using 3D printing techniques, allowing for the creation of scaffolds with precise microarchitecture and composition. PCL scaffolds can provide a suitable microenvironment for cell proliferation and regeneration of damaged tissues or organs. Additionally, PCL can be combined with other biomaterials, drugs, growth factors, and cells to improve its properties and enhance bone healing. The incorporation of bioactive nanomaterials into PCL scaffolds can further enhance mechanical strength, thermal stability, degradation rate, and biomineralization. Furthermore, surface modification strategies can be employed to overcome PCL's hydrophobicity and achieve sustained release of signaling factors, such as bone morphogenetic protein 2 (BMP-2), to modulate cell growth and differentiation. Overall, PCL-based scaffolds offer great potential for bone tissue engineering applications.