Under what circumstances is staining needed in bioprocesses?
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Staining in bioprocesses is crucial for various purposes. It helps in detecting antigens, determining subcellular localization, comparing antigen distribution, identifying infectious organisms, progenitors of neoplastic cells, and inflammatory responses . Staining can also aid in purifying cells based on their antigenic composition, detecting minimal antigen molecules, and estimating antigen concentrations . Standardization of dyes is essential for achieving consistent staining results, with efforts like the European standard EN 12376 focusing on this aspect . Staining processes can be optimized by controlling pre-analytical variables to ensure the integrity of human biopsy specimens and accurate immunohistochemical staining results . Additionally, staining bio-aerosols can provide detailed characteristics and concentration evaluation, aiding in source identification and transport analysis .
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| Papers (5) | Insight |
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| Staining is needed in bioprocesses to evaluate bio-aerosol characteristics and concentrations online, aiding in emission source examination and bio-aerosol transport monitoring using flow cytometry technology. | |
6 Citations | Staining is essential in bioprocesses to prepare biological specimens for microscopic analysis, ensuring standardized results through dye quality control and standardization procedures discussed in the paper. |
2 Citations | Staining is crucial in bioprocesses for identifying specific markers like IMP3 in lung tumors, aiding accurate diagnosis and treatment decisions, especially in distinguishing between different tumor grades. |
| Cell staining is essential in bioprocesses to determine antigen presence, localization, and concentration, aiding in identifying infectious organisms, neoplastic cells, and inflammatory responses, as well as purifying cells based on surface antigens. | |
| Staining is essential in bioprocesses for quantifying cancerous cells in tissues by conjugating antibodies with nanoparticles and utilizing a microscope with a magnetometer for detection. |
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