scispace - formally typeset
Search or ask a question

What are the effects of GABA supplementation on cognitive function? 


Best insight from top research papers

GABA supplementation has been investigated for its effects on cognitive function. There is evidence suggesting that GABA food supplements may have a calming effect, but most of this evidence comes from researchers with potential conflicts of interest . Additionally, GABA receptor modulators have been studied as a potential treatment strategy for Alzheimer's disease, with findings indicating that GABA treatment during early life can improve cognitive function in mice . In a study conducted on young healthy adults, GABA supplementation was found to improve performance in a temporal attention task, specifically in the identification and ordering of visual events that occur in close temporal succession . However, the mechanism of action of GABA food supplements and their effects on cognitive function are still not fully understood, and further research is needed .

Answers from top 5 papers

More filters
Papers (5)Insight
GABA supplementation during early life can significantly improve cognitive function in A beta PP/PS1 mice, according to the provided paper.
The effects of GABA supplementation on cognitive function are not mentioned in the provided paper. The paper is about the effects of dietary taurine-containing jelly supplementation on cognitive function and memory ability of the elderly with subjective cognitive decline.
The paper does not provide information on the effects of GABA supplementation on cognitive function.
The effects of GABA supplementation on cognitive function are not mentioned in the provided paper. The paper is about the cognitive-enhancing effects of Bacopa monnieri.
The paper investigates the effects of GABA supplementation on temporal and spatial attention, but does not specifically address the effects on overall cognitive function.

Related Questions

Does taking GABA supplements increase growth hormone?5 answersTaking GABA supplements has been shown to increase growth hormone (GH) levels. Oral administration of GABA has been found to elevate resting serum GH concentrations. Intravenous administration of GABA also results in a rapid increase in plasma GH levels. Additionally, a single oral dose of GABA has been shown to significantly elevate plasma GH levels. Furthermore, intrathecal injection of GABA has been found to elicit the secretion of GH via the central nervous system. These findings suggest that GABA supplementation can increase GH levels, potentially providing ergogenic benefits.
Does taurine supplementation increase GABA levels in the brain?5 answersTaurine supplementation has been shown to increase GABA levels in the brain. Studies have found that taurine-fed mice have reduced GABAA receptor expression and increased GAD and somatostatin expression in the brain, indicating changes in the GABAergic system. Additionally, taurine-fed mice showed hyperexcitability, which is associated with increased neuronal excitability. These findings suggest that taurine supplementation can lead to an increase in GABA levels in the brain, potentially contributing to its neuroprotective effects.
What is the what is the role of gaba in psychiatric diseases?5 answersThe role of GABA in psychiatric diseases is significant. GABA is the main inhibitory neurotransmitter in the central nervous system (CNS) and plays a crucial role in modulating different processes in the brain. Disruption of the excitatory/inhibitory (E/I) balance, where GABAergic system is the main inhibitory system, is the main cause of many CNS diseases. Abnormalities in the GABAergic system have been associated with cognitive dysfunctions, attention deficits, and various psychiatric disorders such as Alzheimer's disease, Parkinson's disease, Autism spectrum disorder, and Schizophrenia. Additionally, stress-induced reduction of GABAergic neurotransmission in the amygdala, a brain region involved in emotional regulation, may contribute to the development of neuropsychological diseases. The GABAergic system also plays a role in amphetamine-type stimulant (ATS) use disorders, including ATS-induced psychotic disorders and cognitive dysfunctions. Overall, the GABAergic system is involved in the pathogenesis of psychiatric diseases and targeting specific components of this system may provide novel interventions for their treatment.
What is the effect of oral GABA administration on stress and sleep in humans?3 answersOral administration of gamma-aminobutyric acid (GABA) may have positive effects on stress and sleep in humans. Clinical trials have shown that GABA intake can potentially reduce anxiety, improve cognitive function, lower blood pressure, promote growth hormone production, regulate blood glucose levels, and enhance skin health. However, the evidence regarding the effects of oral GABA intake on stress and sleep is mixed. Some studies suggest limited evidence for stress benefits and very limited evidence for sleep benefits of GABA intake. GABA is the main inhibitory neurotransmitter in the brain and is widely used as a supplement to regulate brain function and enhance sleep. It has been found to shorten sleep latency and increase total non-rapid eye movement sleep time. Further research is needed to fully understand the efficacy of oral GABA consumption on stress and sleep.
Is there any literature on the role of GABA in brain cancers?5 answersGABA plays a role in brain cancers. Dysregulation of GABA can have a large impact on the brain and is implicated as an underlying factor in brain diseases. GABA negatively regulates proliferation of pluripotent and neural stem cells. GABA acts in an excitatory manner during early development and is implicated in neurogenesis processes. Glutamine utilization and GABA formation are studied in brain mitochondria, indicating the higher resistance of the GABAergic systems compared to the glutamatergic systems. Excitatory GABA has been shown to activate multiple Ca2+ signaling pathways and contribute to the expression of brain-derived neurotrophic factor (BDNF), which is important for neural development.
What supplements work on GABA receptors?8 answers