scispace - formally typeset
Search or ask a question

What are the pros of using the polymerization method for producing nanoparticles instesd of pre formed polymers? 


Best insight from top research papers

Polymerization methods for producing nanoparticles have several advantages over using preformed polymers. Firstly, polymerization allows for high reproducibility and control over the physicochemical properties of the nanoparticles . This means that the size, shape, and composition of the nanoparticles can be precisely tailored to meet specific needs for different applications . Additionally, polymerization techniques offer the flexibility to use a wide range of monomers and polymerization techniques, such as emulsion, dispersion, and interfacial polymerization, to achieve desired nanoparticle characteristics . Furthermore, polymerization methods enable the use of biodegradable polymers, which are advantageous for biomedical applications . Overall, polymerization methods provide a versatile and cost-effective approach for producing nanoparticles with controlled properties, making them highly suitable for various applications in drug delivery, diagnostics, and catalysis .

Answers from top 4 papers

More filters
Papers (4)Insight
Book ChapterDOI
01 Jan 2013
4 Citations
The advantages of using the polymerization method for producing nanoparticles include high reproducibility, control over physico-chemical properties, low cost, high stability, and wide availability of biodegradable polymers.
The use of polymerization method for producing nanoparticles allows for controlled size, shape, composition, and structural characteristics, providing more opportunities for customization compared to pre-formed polymers.
Polymers offer tailorable structures, rich functionalities, tunable responsiveness, biodegradability, biocompatibility, and low-cost mass production, making them attractive for engineering interactions between nanoparticles.
The advantages of using the polymerization method for producing nanoparticles instead of preformed polymers are not mentioned in the provided information.

Related Questions

Is there a gold standard for polymeric nanoparticle fabrication?5 answersA gold standard for polymeric nanoparticle fabrication involves various methods reported in the literature. Techniques such as direct fabrication of gold nanoparticles (Au NPs) within a polymer matrix using a thermal treatment process, decoration of polymer molds with plasmonic gold nanoparticle arrays, and single-step synthesis of Au nanoparticles in polydimethylsiloxane (PDMS) without external agentshave been proposed. Additionally, UV-induced radical polymerization combined with gold nanoparticle formation in situ within a polymer matrix has been demonstrated as a versatile method for fabricating plasmonic and conductive metal structures. Furthermore, plasmon-driven photopolymerization has been shown to be an efficient method for preparing metal/polymer hybrid nanostructures by triggering the photopolymerization of a monomer using localized surface plasmon resonances of Au nanoparticles.
What are the in situ polymerization methods utilized to incorporating nanoparticles into composites?3 answersIn-situ polymerization methods have been utilized to incorporate nanoparticles into composites. One method involves grafting polyacrylic acid (PAA) membranes onto layered double hydroxide (LDH) nanosheets, resulting in improved compatibility and dispersibility of the nanoparticles. Another method involves the surface modification of detonation nanodiamonds to achieve dispersability in methyl methacrylate, using classical radical polymerization and reversible chain-transfer polymerization. A copper II complex is synthesized and evaluated as a photoredox catalyst/photoinitiator for the radical polymerization of ethylene glycol diacrylate, resulting in the production of polymer nanocomposites containing gold nanoparticles. Conductive polypyrrole (PPy) nanoparticles are in-situ synthesized in the presence of barium titanate (BT) or hydroxylated BaTiO3 (BTOH) particles, and then incorporated into poly(vinylidene fluoride) (PVDF) to prepare composites with high dielectric constant, low dielectric loss, and high breakdown strength. Samarium-doped titanium dioxide (Sm3+-doped TiO2) nanoparticles are incorporated into poly(n-butyl methacrylate) (PBMA) composites using free radical polymerization, resulting in improved flame resistance, thermal stability, and electrical properties.
Is there an application that nanoparticle-reinforced thermoplastic or thermoset composites have demonstrated superior performance?5 answersNanoparticle-reinforced thermoplastic and thermoset composites have demonstrated superior performance in various applications. These composites have shown improved properties such as wear resistance, specific strength/stiffness, corrosion resistance, high temperature strength, and damping properties. In the field of protective applications, para-aramid fiber reinforced composites with thermoplastic matrices have gained interest due to their superior mechanical properties and better energy absorption. Additionally, the application of nanofibers and nanoparticles as reinforcements has been found to enhance the interlaminar fracture toughness, reduce impact-induced damage, and improve compression after impact performance of fiber reinforced composites with brittle thermosetting resins. Furthermore, the use of thermoplastic matrix composites has advantages in terms of repair procedures and recyclability, making them suitable for structural applications.
What are the most common polymeric nanoparticle fabrication techniques?5 answersPolymeric nanoparticles can be fabricated using various techniques such as emulsion polymerization, electrospinning, spin coating, and nanoprecipitation. Emulsion polymerization is commonly used for the fabrication of zero-dimensional (0D) polymeric nanoparticles. Electrospinning is another technique used to produce one-dimensional (1D) polymeric nanofibers. Spin coating is a method employed for the fabrication of two-dimensional (2D) polymeric nanosheets. Nanoprecipitation, on the other hand, is a versatile technique that can be used to construct various polymeric nanostructures, including core-shell morphologies and colloids with equilibrium or out-of-equilibrium morphologies. These fabrication techniques allow for the precise control of the nanostructure and enable the engineering of multifunctional polymeric nanoparticles for a wide range of applications.
How to prepare polymer nanoparticles with UCNPs?5 answersPolymer nanoparticles with UCNPs can be prepared by various methods. One method involves grafting a spiropyran derivative and a naphthalimide derivative onto a polyamino ester to obtain an amphiphilic polymer. This polymer can self-assemble in water to form micellar nanoparticles that exhibit light-controlled fluorescence change, controlled release, and degradability properties. Another method involves cladding UCNPs with a thin cyclodextrin carbon layer through low-temperature cyclodextrin carbonization. This process converts hydrophobic upconversion nanomaterial into a hydrophilic form, improving biocompatibility and stability. Additionally, functionalized UCNPs with a coating of polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) have been synthesized for potential use as contrast agents in swept source optical coherence tomography (SSOCT). The UCNPs with PVP coating showed better results in terms of scattering coefficients and contrast-to-noise ratio. Surface modification of UCNPs with polyacrylic acid (PAA) has also been explored to facilitate interaction with specific bacteria for biosensor applications.
Are there polyester-based nanoparticles fabricated with nanoprecipitation?5 answersPolyester-based nanoparticles fabricated with nanoprecipitation have been reported in the literature. Sokołowska et al. synthesized poly(butylene adipate)-co-(dilinol adipate) (PBA-DLA) nanoparticles using enzymatic synthesis and confirmed their chemical structure using 1H NMR. Yang et al. developed a salt-induced nanoprecipitation method to fabricate polymer nanoparticles with high drug loading, demonstrating the versatility of the technique for different polymers. Yan et al. highlighted the capability of nanoprecipitation in controlling the fabrication of various polymeric nanostructures, including core-shell morphologies. Beck-Broichsitter investigated the effect of organic solvents on the size properties of polymer nanoparticles prepared by nanoprecipitation. Therefore, there are several studies that have successfully utilized nanoprecipitation to fabricate polyester-based nanoparticles.

See what other people are reading

What is the CMC concentration of sodium dodecyl sulfate?
4 answers
The critical micelle concentration (CMC) of sodium dodecyl sulfate (SDS) was investigated in various studies. In one study, the CMC of SDS was determined to be 56.10 mmol/l for an emulsion with a solid content of 22 wt% and a particle size of 115 nm, decreasing to 19.83 mmol/l with an increase in particle size to 494 nm. Another study found that SDS concentrations ranging from 0.1% to 1.0% w/v challenged the system's capacity, with complete clearance achieved from 0.1% samples in 30 minutes, while 100% clearance from 0.5% samples required 120 minutes of extraction. Additionally, the presence of amino acids was shown to affect the CMC of SDS, with a depression in CMC at low amino acid concentrations and an increase at higher concentrations due to altered interactions between the surfactant molecules.
What is a polymer?
5 answers
A polymer is a macromolecule composed of repeating units bonded together, typically through covalent bonds, forming a large molecular structure with high molecular weight. Polymers, often referred to as plastics in industries, exhibit diverse properties such as biocompatibility, biodegradability, and structural variability based on factors like backbone structure and crystallinity. These versatile materials have found extensive applications in various fields, including medicine, where they are utilized in medical devices like implants, drug delivery carriers, and tissue scaffolds. The properties and characteristics of polymers can be tailored to specific needs, making them valuable for a wide range of applications. In the realm of drug delivery systems, polymers play a crucial role in protecting drugs, controlling their release, and enhancing stability.
What are the differences between a structural compisite material and a non strctural one?
5 answers
Structural composite materials are designed to bear high loads without deformation or fracturing, commonly used in applications like bone fracture repairs and orthopedic devices. These materials typically consist of solid composite sections coupled with structural foams to reduce weight and prevent delamination under stress. In contrast, non-structural composite materials lack the same load-bearing capabilities and are not specifically engineered for high-stress applications. They may incorporate metal-type layers for conductivity in aircraft components. The key distinction lies in the intended use and design features, with structural composites prioritizing strength and durability for demanding applications, while non-structural composites may focus on other properties like conductivity or aesthetics.
What is electrochemical OCP method to study corrosion behavior of Mg alloys in corrosive solutions?
10 answers
The electrochemical Open Circuit Potential (OCP) method is a widely used technique for studying the corrosion behavior of magnesium (Mg) alloys in various corrosive solutions. This method involves measuring the steady-state potential of a corroding metal or alloy in an electrolyte without applying any external current. The OCP value provides insights into the thermodynamic tendency of the metal to corrode in the given environment. Research on Mg alloys has demonstrated the application and significance of OCP measurements across different corrosive media and alloy compositions. For instance, studies have shown that the corrosion rates of Mg alloys can vary significantly with the composition of the corrosive solution, such as NaCl, Na2SO4, and molten salts, as well as with the alloy's microstructural characteristics. The OCP method has been instrumental in identifying the electrochemical activity and corrosion initiation points on Mg alloys in chloride-containing solutions, where the corrosion process was observed to initiate locally and propagate over the surface. Similarly, the OCP measurements have highlighted the influence of fluoride ions in forming protective MgF2 films on Mg alloys, leading to a continuous increase in weight due to the corrosion product layer formation. Moreover, the OCP method has been applied to evaluate the corrosion resistance of Mg alloys with different treatments and microstructures, such as as-cast, solid-solution treated, and as-extruded alloys, revealing how microstructural changes can impact corrosion behavior. In biomedical applications, the OCP measurements have provided valuable data on the corrosion resistance of Mg alloys in simulated body fluids, aiding in the development of Mg-based biomaterials. Additionally, the OCP method has been used to assess the effectiveness of surface treatments and coatings in improving the corrosion resistance of Mg alloys. For example, sol-gel coatings on Mg alloys have been shown to significantly enhance corrosion resistance by sealing surface defects and cracks, as evidenced by OCP measurements. In summary, the OCP method serves as a crucial tool in understanding the corrosion mechanisms of Mg alloys, guiding the optimization of alloy compositions, microstructures, and surface treatments to enhance their corrosion resistance in various environments.
How does the interface between an electroconductive scaffold and medium behave under applied electrical stimulation?
5 answers
The interface between an electroconductive scaffold and medium under applied electrical stimulation influences cell behavior and differentiation. Conductive scaffolds, such as chitosan-polyaniline substrates, when combined with electrical stimulation, promote neural-like phenotypes in stem cells, enhancing nerve tissue engineering outcomes. Carbon nanofiller-based scaffolds, synchronized with electrical stimulation, show promise in nerve tissue repair due to their excellent electrical properties and biocompatibility. In cardiac tissue engineering, external electrical stimulation in conductive scaffolds affects cardiomyocyte behavior positively, leading to improved function and tissue construct optimization. Additionally, electroconductive scaffolds combined with electrical stimulation guide adipose-derived stem cells towards neurogenic differentiation, indicating potential applications in nerve injury regeneration. These findings collectively highlight the significant impact of the electroconductive scaffold-medium interface under electrical stimulation on directing cell behavior and differentiation for tissue engineering applications.
What is the significance of liposomal nanodrugs?
5 answers
The significance of liposomal nanodrugs lies in their innovative approach to drug delivery, offering a multitude of benefits across various medical applications. Liposomal nanoparticles, by encapsulating drugs within lipid bilayers, enhance the therapeutic efficacy while minimizing toxicity, a crucial advancement in nanopharmacology, especially in antitumor treatments. These liposomal forms are characterized by their ability to reduce side effects, improve stability, and increase the antitumor activity of encapsulated agents, thereby allowing for prolonged drug action and the treatment of drug-resistant tumors. In cancer therapy, liposomal nanoparticles serve as an ideal platform for systemic immune modulator delivery, addressing the limitations of traditional cancer treatments by avoiding tumor metastasis and relapse. Their biocompatibility, structural versatility for ligand anchoring, and stimuli-responsiveness make them suitable for clinical and industrial applications. Furthermore, liposomes offer targeted drug delivery and improved pharmacokinetics, leading to enhanced bioavailability and reduced drug toxicity, which is essential for chronic disease treatment and improving patient compliance. The development of liposomes as drug carriers also extends to the delivery of both hydrophilic and hydrophobic agents, showcasing their versatility and higher biodegradability, which is particularly significant in cancer therapy. Their structural similarity to biological membranes allows for high skin permeation, making them useful for topical drug delivery. Additionally, liposomal nanoparticles have been employed to overcome challenges such as antibiotic resistance and poor drug solubility, demonstrating enhanced antibacterial actions while minimizing toxicity. In the food and medicinal industries, liposomes improve the bioavailability of nutrients and drugs, offering a high therapeutic index and protecting bioactive food compounds from spoilage. Lastly, liposome nanoparticles (LNPs) combine the advantages of liposomes and inorganic/organic nanoparticles, providing a multifunctional system for diverse biomedical applications, including controlled drug release and biological imaging. Collectively, these attributes underscore the significance of liposomal nanodrugs in advancing therapeutic strategies and patient care.
What is the use of synthetic biology for bacterial cellulose production and modification?
5 answers
Synthetic biology plays a crucial role in enhancing bacterial cellulose (BC) production and modification. Studies have shown that genetic modifications in BC-producing strains can lead to improved BC properties. Additionally, the use of modified carbon sources and engineered strains has been explored to increase BC yield and productivity while minimizing production costs. Furthermore, synthetic biology techniques have been utilized to directly synthesize BC with specific functionalities, such as incorporating photosensitizers for light-triggered bactericidal activity in wound dressing applications. These advancements highlight the potential of synthetic biology in tailoring BC properties for various applications, ranging from biodegradable composites to biomedical purposes.
What factors contribute to the lack of self-healing properties in dual crosslinked adhesive hydrogels?
5 answers
The lack of self-healing properties in dual crosslinked adhesive hydrogels can be attributed to several factors. One key factor is the predominant use of chemically crosslinked networks in hydrogels, which can hinder self-healing capabilities. Additionally, the complexity of the preparation process in some hydrogels may also contribute to the lack of efficient self-healing properties. Furthermore, poor mechanical properties and weak self-healing ability are common challenges faced by hydrogels based on natural polymers, limiting their self-healing capabilities. To address these issues, researchers have explored strategies such as incorporating multiple dynamic non-covalent bonds and physical crosslinking to enhance self-healing abilities while maintaining mechanical strength in hydrogels.
What are the potential health effects of using polymethylmethacrylate (PMMA) in various applications?
5 answers
The use of polymethylmethacrylate (PMMA) in various applications can have both positive and negative health effects. PMMA is biocompatible, stable, and non-toxic, making it suitable for medical and dental applications. However, PMMA lacks antimicrobial properties, thermal conductivity, and radiopacity, limiting its applications in dentistry. Incorporating nanoparticles like graphene, silver, TiO2, ZnO, and SiO2/Ag can enhance PMMA's antimicrobial potential. In dental applications, combining PMMA with Al2O3 nanoparticles can improve mechanical properties and wear resistance, with gamma radiation ensuring product sterility without significant adverse effects. On the other hand, exposure to methyl methacrylate (MMA), a component of PMMA, can lead to respiratory and skin irritation in humans and animals, although it is not considered carcinogenic.
Sources of β-Cyclodextrin ?
4 answers
β-Cyclodextrin (β-CD) can be sourced from various materials. One study demonstrated the production of β-CD using jackfruit seed bran (JSB) as an alternative starch substrate, showing promising results for β-CD production. Additionally, β-CD has been explored as a green catalyst for synthesizing bioactive heterocyclic moieties from easily available precursors, highlighting its versatility and eco-friendly nature. Furthermore, β-CD-based polymers and nanosystems have been extensively studied for water purification applications, showcasing their effectiveness in removing impurities from wastewater through host-guest interactions and modification reactions. Moreover, β-CD has been utilized in the synthesis of nanocomposite derivatives with various nanoparticles, enhancing their biocompatibility and molecular recognition properties, thus expanding their potential applications in chemistry and biology.
Cancer cell membrane borospherene for targeted delivery
5 answers
Cancer cell membrane-coated boron nitride nanomaterials have shown great potential for targeted drug delivery in cancer therapy. These biomimetic nanoplatforms combine the advantages of boron nitride nanoparticles (BN) with the targeting ability of cancer cell membranes (CCM). By encapsulating BNs with cancer cell membranes, these nanoplatforms exhibit enhanced dispersibility, cytocompatibility, and homologous targeting of cancer cells, leading to increased cellular uptake and improved cytotoxicity against cancer cells. Furthermore, the incorporation of cancer cell membrane onto BN nanospheres has shown to enhance tumor-selective drug delivery, resulting in efficient tumor inhibition. This innovative approach holds promise for personalized and targeted cancer therapy, offering a potential solution to the challenges of drug delivery in cancer treatment.