scispace - formally typeset
Search or ask a question

What can low neutorphils levels mean, that stay low for 3 years? 


Best insight from top research papers

Low neutrophil levels persisting for an extended period, such as 3 years, can indicate a condition known as late-onset neutropenia, which has been observed in very low birth weight (VLBW) infants . This phenomenon is characterized by a decrease in absolute neutrophil count (ANC) at a postnatal age of ≥3 weeks, with the duration of neutropenia typically lasting around 1.7 weeks. Late-onset neutropenia is often detected in stable, growing VLBW infants and is associated with anemia of prematurity and marked reticulocytosis. Despite the low neutrophil levels, infants with late-onset neutropenia are usually asymptomatic and do not exhibit signs of sepsis, suggesting that this condition may not have adverse effects on these infants' health .

Answers from top 4 papers

More filters
Papers (4)Insight
Not addressed in the paper.
Low neutrophil levels persisting for 3 years in limited disease small-cell lung cancer patients may indicate a poor prognosis, potentially leading to worse outcomes such as decreased survival rates.
Not addressed in the paper.
Open accessJournal Article
Aurelio Bruno, Inci Ayhan, Alan Johnston 
8 Citations
Not addressed in the paper.

Related Questions

What can low neutorphils levels mean, that stay low for 3 years in 28 year old woman?5 answersChronic mild neutropenia in adults, especially in young patients like a 28-year-old woman, can be associated with various conditions. Neutrophil levels are crucial for immune function, and persistently low levels may indicate an underlying immunodeficiency or autoimmune condition. Additionally, a low neutrophil count can lead to increased susceptibility to infections. Studies have shown that neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammation and can be linked to adverse outcomes in different conditions, including chronic kidney disease (CKD). Therefore, in a young woman with persistently low neutrophil levels for 3 years, further investigations are warranted to assess for potential underlying autoimmune disorders, immunodeficiencies, or chronic inflammatory conditions that could be impacting her neutrophil count and overall health.
What’s the range for thc levels in the blood to drop below 3.5 ng.?5 answersThe range for THC levels in the blood to drop below 3.5 ng can vary based on different factors such as frequency of cannabis use and time since last use. Studies have shown that THC concentrations in blood can fluctuate significantly postmortem, with median concentrations ranging from 1.9 ng/mL to 13.8 ng/mL. Additionally, research on serum samples from cannabis users revealed that THC and its metabolites could still be detected 24-48 hours after discontinuation of cannabis smoking, with concentrations ranging from 1.3-6.4 ng/mL for THC and 0.5-2.4 ng/mL for 11-hydroxy-THC in heavy users. These findings suggest that the timeframe for THC levels to drop below 3.5 ng in blood can be influenced by individual usage patterns and metabolism, making it challenging to pinpoint an exact range without considering specific circumstances.
What do low bilirubin levels mean?4 answersLow bilirubin levels, known as hypobilirubinemia, have been linked to various health implications. Research suggests that low serum bilirubin levels are associated with increased risks of kidney function decline, cardiovascular complications, stroke, and impaired cognitive function. Specifically in kidney transplant patients, lower bilirubin levels are correlated with higher risks of graft loss, graft failure, rejection, and mortality. In IgA nephropathy patients, low bilirubin levels are linked to a higher likelihood of reaching combined renal endpoints, indicating disease progression. These findings highlight the importance of monitoring bilirubin levels, especially in individuals with conditions like diabetes, hypertension, and kidney diseases, as low bilirubin levels may serve as a marker for increased health risks and poorer outcomes.
What can be the reasons for low T3 in CSF?4 answersLow T3 in cerebrospinal fluid (CSF) can be caused by several factors. One possible reason is the disruption of the local intracerebral conversion process, leading to increased levels of reverse triiodothyronine (rT3) in the CSF. Another potential cause is the development of isolated syndrome in the brain, characterized by specific thyroidal metabolic disorders, which the authors propose to call the cerebral low T3 syndrome. Additionally, low T3 in CSF can be associated with neurocritical conditions, such as acute subarachnoidal hemorrhage and neurocritical events, leading to a depression of thyroidal metabolism. It is important to note that these studies focus on specific patient populations and conditions, and further research is needed to fully understand the mechanisms behind low T3 in CSF.
How long can you live with a low platelet count?5 answers
When should you go to the ER for low oxygen levels?6 answers

See what other people are reading

What are the factors that contribute to good air quality in public markets?
4 answers
Factors contributing to good air quality in public markets include pedestrian traffic monitoring, proper layout of functional areas, well-designed ventilation systems, and public and private investment motivated by housing price growth. Monitoring pedestrian traffic helps identify pollutant sources, while addressing layout and ventilation issues can mitigate air quality problems. Additionally, the positive impact of housing price growth on air quality improvement is more pronounced in developed areas, leading to better environmental protection and enhancement efforts. Regulatory programs like the Clean Air Markets initiatives also play a crucial role in reducing air pollution from various sources, including public markets. These combined efforts can significantly enhance air quality in public markets, benefiting the health of users and stakeholders.
What do higher fixation rates in eye-tracking studies imply?
5 answers
Higher fixation rates in eye-tracking studies have been linked to improved memory retention. Additionally, fixation rates can indicate mental workload, with increased fixation frequency correlating with regions related to vision and memory in the brain. Fixation patterns can also reveal differences in eye movement efficiency based on contrast polarity and lighting conditions. Moreover, fixation patterns have been utilized to assess confusion levels in users interacting with persona profiles, highlighting the importance of consistent informational elements to reduce confusion. Eye-tracking studies on YouTube advertising have shown that higher fixation rates on ad banners do not necessarily translate to better recall, emphasizing the need for advertisers to carefully select placement locations for optimal engagement.
What are the effects when students lacks comfort room?
5 answers
When students lack comfort in their classroom environment, it can have various negative effects on their well-being and academic performance. Issues such as inadequate thermal comfort, poor indoor air quality, and discomfort due to extreme temperatures can lead to symptoms like tiredness, reduced productivity, and even health problems among students. Research shows that students' perception of the indoor environment significantly impacts their academic performance and overall health. Furthermore, discomfort in classrooms can result in dissatisfaction among students, affecting their learning experience and efficiency. To address these challenges, it is crucial to improve indoor environmental conditions in educational buildings by considering factors like thermal comfort, air quality, and proper ventilation systems to ensure students' well-being and enhance their learning outcomes.
How effective are bi-specifics in treating multiple myeloma?
5 answers
Bispecific antibodies (BsAbs) have shown significant effectiveness in treating multiple myeloma (MM). BsAbs targeting B-cell maturation antigen (BCMA), GPRC5D, or FcRH5 have demonstrated overall response rates of approximately 60%-70%, with a high proportion of patients achieving very good partial or complete responses. These therapies activate the patient's T-cells to target tumor cells, showing promising results in relapsed/refractory MM patients. BsAbs have been found to induce dose-dependent cell killing of myeloma cells both in vitro and in vivo, leading to tumor regression in xenograft models. Despite their efficacy, BsAbs can lead to adverse events like cytokine release syndrome and infections, emphasizing the importance of monitoring and infectious prophylaxis during treatment. Overall, BsAbs offer a novel and potent therapeutic option for MM patients, with ongoing studies aiming to further enhance their efficacy and safety profiles.
How does low level of concentration affect cognitive function and productivity in individuals?
5 answers
A low level of concentration can significantly impact cognitive function and productivity in individuals. Research has shown that concentration plays a crucial role in achieving maximum and faster results in work. When individuals are not concentrating, their memory test scores tend to be lower, leading to a decrease in correct answer rates and overall cognitive performance. Additionally, studies have indicated that maintaining a high level of concentration is essential for intellectual productivity, as distractions or lack of focus can hinder task performance. Therefore, it is vital to understand the influence of factors like indoor air quality and environmental conditions on concentration levels to optimize cognitive function and productivity in individuals.
How do kitchen facilities impact the productivity and efficiency of a workplace?
5 answers
Kitchen facilities play a crucial role in impacting the productivity and efficiency of a workplace. Ergonomically designed kitchens with proper work surfaces, storage spaces, and efficient work plans can enhance worker performance. Factors such as workplace temperature, air quality, and sanitation also significantly influence workers' performance standards. Additionally, the interaction between hygiene and ergonomics in kitchen design is essential for maintaining productivity and staff efficiency. Indoor air quality, including temperature and air contaminants, directly affects the physical health of staff, emphasizing the need for proper ventilation systems in kitchens. Moreover, providing complementary meals or food services at the workplace can improve employees' dietary intake, lifestyle patterns, and overall quality of life, thereby potentially enhancing their outcomes.
How to select a paper for a review?
5 answers
To select a paper for review, various methods and considerations can be employed. One approach involves structuring the selection process with iterations, starting with a primary selection and then expanding, reducing, and analyzing the papers to reach a final selection, as described in one study. Another aspect to consider is author diversity, which can be crucial in preventing bias in the review process. Methods like Overall Diversity, Round Robin Diversity, and Multifaceted Diversity take into account multiple demographic characteristics to recommend papers, enhancing diversity without significantly decreasing utility. Additionally, utilizing frameworks based on empirical risk minimization can help in learning the community's aggregate mapping of criteria scores to improve consistency in peer review recommendations.
What are the potential clinical implications of HRV in predicting fear of height?
5 answers
Heart Rate Variability (HRV) holds potential clinical implications in predicting fear of height. Studies have shown that HRV can be utilized to assess anxiety disorders, as it reflects autonomic modulation and can indicate cardiac electrical instability due to autonomic imbalance. Furthermore, HRV has been linked to predicting anxiety traits and affective states. In the context of fear of heights, HRV has been explored in relation to virtual reality exposure therapy (VRET) for acrophobia. The findings suggest that HRV can differentiate between individuals with and without fear of heights, with significant differences in hemodynamic responses observed during fear-inducing VR scenarios. Therefore, HRV could serve as an objective indicator for predicting fear responses related to heights, aiding in the assessment and treatment of acrophobia.
What is the relation between the fear of height and HRV coherence?
5 answers
The fear of height can impact Heart Rate Variability (HRV) coherence. Research has shown that fear responses, such as fear of falling or fear of height, can lead to changes in autonomic nervous system activity, affecting HRV coherence. Fear of falling, for instance, can influence postural responses and balance control mechanisms. Studies have demonstrated that fear can induce physiological changes, such as increased sympathetic activity towards blood vessels, resulting in vasoconstriction and decreased spectral coherence in response to stimuli like postural changes. Therefore, fear-related responses, including fear of height, can alter autonomic nervous system activity, reflected in HRV coherence changes, highlighting the intricate relationship between psychological factors like fear and physiological responses like HRV coherence.
How effective is rituximab in managing the symptoms of Evans syndrome compared to other available treatments?
5 answers
Rituximab has shown effectiveness in managing Evans syndrome symptoms compared to other available treatments. Evans syndrome, characterized by autoimmune hemolytic anemia, immune thrombocytopenia, and sometimes immune neutropenia, is often treated with corticosteroids, intravenous immunoglobulins, rituximab, and splenectomy for refractory cases. Rituximab, a monoclonal antibody, is commonly used as a second-line treatment for Evans syndrome, especially in cases where patients are unresponsive to steroids. Studies suggest that rituximab, along with corticosteroids and IVIG, can lead to a slow but significant improvement in anemia and thrombocytopenia in Evans syndrome patients. Despite continuous advancements in treatment options, the management of Evans syndrome remains challenging due to its rarity and the need for further improvements in patient outcomes.
Rituximab in the treatment of Evans syndrome compared to other available treatments?
5 answers
Rituximab is a crucial component in the treatment of Evans syndrome, a rare autoimmune disorder characterized by the co-occurrence of immune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA). It is considered a second-line treatment option for Evans syndrome, especially for patients who are refractory to steroids. The management of Evans syndrome often involves corticosteroids, rituximab, splenectomy, and supportive therapies. Additionally, rituximab has shown efficacy in cases of Evans syndrome with common variable immunodeficiency, providing a durable response in refractory situations. Despite the progress in treatment options, including rituximab, mortality rates in Evans syndrome remain higher than those in isolated autoimmune cytopenias, highlighting the ongoing need for improved management strategies.